7145-73-5Relevant articles and documents
Synthesis and activity of 2-(sulfonamido)methylcarbapenems: Discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore
Wilkening,Ratcliffe,Wildonger,Cama,Dykstra,DiNinno,Blizzard,Hammond,Heck,Dorso,St Rose,Kohler,Hammond
, p. 673 - 678 (2007/10/03)
A series of 1β-methyl carbapenems substituted at the 2-position with lipophilic, acyclic and cyclic (sulfonamido)methyl groups was prepared and evaluated for activity against resistant gram-positive bacteria. From these studies, the 1,8-naphthosultamyl gr