71450-13-0

Basic information

• Product Name: L-Phe-L-Met-NH₂ formate
• Synonyms: L-Phe-L-Met-NH₂ formate
• CAS NO: 71450-13-0
• Molecular Weight: 341.431
• Mol File: 71450-13-0.mol

Chemical Properties

• CAS DataBase Reference: L-Phe-L-Met-NH₂ formate(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phe-L-Met-NH₂ formate(71450-13-0)
• EPA Substance Registry System: L-Phe-L-Met-NH₂ formate(71450-13-0)

Safety Data

• Hazardous Substances Data: 71450-13-0(Hazardous Substances Data)

Upstream product

• 60117-24-0 H-Tyr-Gly-Gly-Phe-Leu-NH₂ 
• 4510-08-1 L-methioninamide 
• 64-18-6 formic acid 
• 71450-10-7 benzyl N-((1S)-2-[(1S)-1-(aminocarbonyl)-3-(methylsulfanyl)propyl]amino-1-benzyl-2-oxoethyl)carbamate 

Downstream Products

• 64563-22-0 L-Phe-L-MetNH₂ 

Relevant articles and documents

Removal of some commonly used protecting groups in peptide syntheses by catalytic transfer hydrogenation with formic acid and 10% palladium on carbon

It is shown that HCOOH, a good solvent for most peptides, can be conveniently used as a hydrogen donor for catalytic transfer hydrogenation with less expensive 10% Pd on C when compared to palladium black. The protecting groups that are being successively removed include the Nα-benzyloxycarbonyl, Nε-2-chlorobenzyloxycarbonyl, C-terminal benzyl ester, O-benzyl ether of O-benzyltyrosine, serine or threonine, nitro of nitroarginine and Nim-benzyloxymethyl of histidine.

Catalytic Transfer Hydrogenation in Pepetide Synthesis: Synthesis of 5- and 5-enkephalins

The simplicity in the removal of N-protecting groups like benzyloxycarbonyl employed in peptide synthesis by catalytic transfer hydrogenation at room temperature using formic acid in presence of palladium black has been demonstrated by the synthesis of the opioid pentapeptides 5- and 5-enkephalins.