714569-16-1

Usage

Structure

A quinoxalinone derivative with a hydroxymethyl group

Physical form

White to off-white solid

Molecular weight

174.188 g/mol

Potential applications

Medicinal and pharmaceutical chemistry, biological activities

Use as building block

Synthesis of other chemical compounds

Upstream product

• 714569-12-7 N-(2-nitrophenyl)-O-benzyl-D-serine methyl ester 

Downstream Products

• 714569-22-9 (3R)-3-(aminomethyl)-4-[(3,4-dichlorophenyl)sulfonyl]-3,4-dihydroquinoxalin-2(1H)-one 

Relevant academic research and scientific papers

BENZODIAZEPINE AND BENZOPIPERAZINE ANALOG INHIBITORS OF HISTONE DEACETYLASE

This invention relates to compounds for the inhibition of histone deacetylase More particularly, the invention provides for compounds of formula (I): wherein A, B, D, E, X1, X2, X3, X4 and n are as defined in the specification A method of inhibiting histone deacetylase in a cell, the method comprising contacting the cell with a compound of formula (I), in an amount sufficient to inhibit histone deacetylase, is also disclosed.

2-QUINOXALINONE DERIVATIVES AS BRADYKININ ANTAGONISTS AND NOVEL COMPOUNDS

2-Quinoxalinone derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.

NOVEL QUINOXALINONE DERIVATIVES AS BRADYKININ B1 ANTAGONISTS

2-Quinoxalinone derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.