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Trans-4-Propylcyclohexylacetic acid, also known as PCAA, is a synthetic compound belonging to the cyclohexylcarboxylic acid class. It is recognized for its ability to inhibit the production of inflammatory mediators, making it a significant pharmaceutical intermediate in the synthesis of anti-inflammatory and analgesic drugs.

71458-18-9

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71458-18-9 Usage

Uses

Used in Pharmaceutical Industry:
Trans-4-Propylcyclohexylacetic acid is used as a pharmaceutical intermediate for the synthesis of various drugs, particularly in the production of anti-inflammatory and analgesic medications. It is valued for its ability to inhibit the production of inflammatory mediators, contributing to the treatment of inflammatory conditions.
Used in Neurodegenerative Disease Treatment:
Trans-4-Propylcyclohexylacetic acid is used as a potential therapeutic agent for treating neurodegenerative diseases, leveraging its ability to modulate inflammatory pathways that are implicated in such conditions.
Used in Anticancer Applications:
Trans-4-Propylcyclohexylacetic acid is used as an anti-cancer agent, being studied for its potential to target and inhibit processes that contribute to the development and progression of cancer.
Used in Medicinal Chemistry and Drug Development:
Trans-4-Propylcyclohexylacetic acid is used as a valuable compound in the field of medicinal chemistry and drug development due to its versatile properties and potential applications in various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 71458-18-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,4,5 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 71458-18:
(7*7)+(6*1)+(5*4)+(4*5)+(3*8)+(2*1)+(1*8)=129
129 % 10 = 9
So 71458-18-9 is a valid CAS Registry Number.

71458-18-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-propylcyclohexyl)acetic acid

1.2 Other means of identification

Product number -
Other names trans-4-propylcyclohexylacetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71458-18-9 SDS

71458-18-9Relevant academic research and scientific papers

Liquid crystalline compounds based on 1,4-disubstituted but-1-YNE

Dabrowski,Dziaduszek,Szczucinski,Parka

, p. 201 - 215 (2007/10/02)

Liquid crystalline compounds containing the -CH2CH2-C ≡ C- inter-ring linkage between cyclohexane and benzene rings belonging to four homologous series have been prepared. Their mesogenic, viscous, dielectric, optical, and dielectrooptical properties were investigated and compared with the properties of analogous compounds with the -CH2CH2- or -C ≡ C- bridge groups. The mesogenic and physical properties of the compounds with the -CH2CH2-C ≡ C- linkage group are intermediate between properties of the compounds with -C ≡ C- and the properties of the compounds with -CH2CH2- group, except that their clearing points are lower and viscosity is higher.

SYNTHESIS AND SOME PHYSICAL PROPERTIES OF 1-CYCLOHEXYL-2-(4 double prime -HALOBIPHENYL-4 prime -yl)ETHANES.

Takatsu,Takeuchi,Sato

, p. 345 - 355 (2007/10/02)

A series of 1-(trans-4 prime -n-alkylcyclohexyl)-2-(4 double prime -halobiphenyl-4 prime -yl)ethanes, which show nematic phases, was prepared. Their transition temperatures, enthalpies and entropies were measured. Their bulk viscosities, birefringences and dielectric constants were determined by extrapolation. The bulk viscosity as a function of the third power of the van der Waals radius of the halogeno group, the birefringence as a function of the van der Waals radius of the halogeno group, and the dielectric constants as a function of the dipole moment of the halogeno group are discussed for the 1-(trans-4 prime -n-propylcyclohexyl)-2-(4 double prime -halobiphenyl-4 prime -yl)ethanes.

1-(TRANS-4 prime -N-ALKYLCYCLOHEXYL)-2-(4 double prime -CYANOPHENYL)ETHANES - A NEW SERIES OF STABLE NEMATOGENS OF POSITIVE DIELECTRIC ANISOTROPY.

Carr,Gray,McDonnell

, p. 13 - 28 (2007/10/02)

The synthesis and some important properties of the 1-(trans-4 prime -n-alkylcyclohexyl)-2-(4 double prime -cyanophenyl)ethanes - where n-alkyl equals C//1 to C//7 - are described.

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