71459-54-6

Upstream product

• 157793-52-7 p-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphonate 
• 50571-26-1 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 
• 106-48-9 4-chloro-phenol 
• 17331-53-2 3'-O-benzoylthymidine 
• 65062-61-5 4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphate triethylammonium salt 
• 65062-60-4 4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphate 

Relevant academic research and scientific papers

31p NMR studies on oxidative transformations of aryl nucleoside h-phosphonate diesters

Various aspects of oxidative coupling of nucleoside aryl H-phosphonate diesters with nucleosides to produce important synthetic intermediates in the phosphotriester approach to oligonucleotide synthesis, dinucleoside aryl phosphotriesters, was investigated. Copyright

6-Nitrobenzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (NBOP): A new coupling reagent in oligonucleotide synthesis

6-Nitrobenzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (NBOP, 2) has been demonstrated as an efficient coupling reagent in oligonucleotide synthesis. The reagent is stable and gives high coupling yields without any side products.