7147-37-7

Basic information

• Product Name: 6,8-diaminopyrimido[5,4-g]pteridine-2,4(1H,3H)-dione
• CAS NO: 7147-37-7
• Molecular Formula: C₈H₆N₈O₂
• Molecular Weight: 246.1856
• Mol File: 7147-37-7.mol
• Article Data: 1

Chemical Properties

• Density: 1.852g/cm³
• Refractive Index: 1.851
• CAS DataBase Reference: 6,8-diaminopyrimido[5,4-g]pteridine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6,8-diaminopyrimido[5,4-g]pteridine-2,4(1H,3H)-dione(7147-37-7)
• EPA Substance Registry System: 6,8-diaminopyrimido[5,4-g]pteridine-2,4(1H,3H)-dione(7147-37-7)

Safety Data

• Hazardous Substances Data: 7147-37-7(Hazardous Substances Data)

Upstream product

• 1004-38-2 2,4,6-triaminopyrimidine 
• 87-39-8 violuric acid 
• 67-52-7 BARBITURIC ACID 
• 1006-23-1 5-nitroso-2,4,6-triaminopyrimidine 
• 593-85-1 diguanidine carbonate 
• 61066-33-9 pyrimidine-2,4,5,6(1H,3H)-tetraone 
• 1004-74-6 2,4,5,6-tetraaminopyrimidine 

Downstream Products

• 5807-13-6 1,3,6,8-tetrahydro-2,4,5,7-pyrimido<5,4-g>pteridinetetrone 

Relevant articles and documents

Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening

The oxidation reactions of 5-aminopyrimidine derivatives in dimethyl sulphoxide (DMSO) were studied. The DMSO solutions of the studied compounds became deeply coloured within a few hours or days. The oxidation products can undergo further condensation reactions with the starting pyrimidines to yield bipyrimidines and/or pyrimidopteridines. The reaction mechanism of the oxidation-condensation reaction was also supported by reactions of the 5-aminopyrimidines with alloxan (2,4,5,6-tetraoxopyrimidine). DMSO is often used as the solvent in in vitro tests of biological activities, but it is also an oxidising agent and may react with solute molecules and significantly affect the quality of the generated biochemical data.