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7147-66-2

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7147-66-2 Usage

General Description

1,3-bis(2-benzimidazole)propane, also known as BBP, is a chemical compound used in the production of flame retardants, corrosion inhibitors, and as a ligand for metal coordination complexes. It is a member of the bis(benzimidazole) family, known for their high thermal and chemical stability. BBP has been shown to have potential application in the medical field as well, as it exhibits anti-tumor and anti-inflammatory properties. Additionally, its unique molecular structure and properties make BBP a promising candidate for various industrial and technological applications, including in the development of advanced materials and polymers. However, further research is needed to fully understand and explore the potential uses and benefits of 1,3-bis(2-benzimidazole)propane.

Check Digit Verification of cas no

The CAS Registry Mumber 7147-66-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7147-66:
(6*7)+(5*1)+(4*4)+(3*7)+(2*6)+(1*6)=102
102 % 10 = 2
So 7147-66-2 is a valid CAS Registry Number.

7147-66-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[3-(1H-benzimidazol-2-yl)propyl]-1H-benzimidazole

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7147-66-2 SDS

7147-66-2Relevant articles and documents

Bisbenzimidazole Derivatives as Potential Antimicrobial Agents: Design, Synthesis, Biological Evaluation and Pharmacophore Analysis

Ersan, Ronak Haj,Bolelli, Kayhan,Gonca, Serpil,Dogen, Aylin,Burmaoglu, Serdar,Algul, Oztekin

, p. 149 - 158 (2021/05/13)

In an attempt to design and synthesize a potent class of antimicrobials, 1,2-phenylenediamine derivatives were reacted with various aliphatic and heteroaliphatic dicarboxylic acids to generate a small library of 26 head-to-head bisbenzimidazole compounds (16 – 42) using the polyphosphoric acid method. These compounds were screened for their antibacterial activity and their antifungal activity. Compound 25 showed maximum potency against both Gram-positive and Gram-negative bacterial strains with minimum inhibitory concentration (MIC) values in the range of 7.81 – 31.25 μg/mL. In particular, it showed the maximum MIC values of 7.81 μg/mL against Gram-negative bacteria, which was four-fold more active than the standard drug ampicillin (MIC = 32.25 μg/mL). Compound 19 was found to be the most active against S. aureus with a MIC value of 3.90 μg/mL, whereas the remaining compounds showed only low-to-moderate activity. Furthermore, all compounds exhibited low activity against all fungal strains in comparison to the standard drug fluconazole. I addition, pharmacophore hypotheses were generated to analyze structure–activity relationships between the molecular structures and antimicrobial activities on E. coli. This pharmacophore model can be useful in order to design new antimicrobial drugs. It can be suggested that the substitution of a phenyl ring at the 5/6 and 5′/6′ positions in symmetric bisbenzimidazole derivatives produces compounds with promising antimicrobial activity.

CuO nano-particles supported on silica, a new catalyst for facile synthesis of benzimidazoles, benzothiazoles and benzoxazoles

Inamdar, Suleman M.,More, Vinod K.,Mandal, Sisir K.

, p. 579 - 583 (2013/02/23)

A facile synthetic route for benzimidazoles, benzothiazoles and benzoxazoles comprising the reaction of corresponding o-phenylenediamine, o-aminothiophenol and o-aminophenol with various aldehydes using silica supported nano-copper (II) oxide as a catalyst has been described. The catalyst exhibited clean reaction profile with excellent yields in a short reaction time. The catalyst can be recycled effectively after use.

Synthesis and anti-HIV activity of [ddN]-[ddN] dimers and benzimidazole nucleoside dimers

Li, Guo-Rui,Liu, Jun,Pan, Qin,Song, Zhi-Bin,Luo, Feng-Ling,Wang, Shao-Ru,Zhang, Xiao-Lian,Zhou, Xiang

scheme or table, p. 2200 - 2208 (2010/07/17)

In an attempt to combine the HIV-inhibitory capacity of different 2′,3′-dideoxynucleoside (ddN) analogs, we have designed and synthesized several dimers of [AZT]-[AZT] and [AZT]-[d4T]. In addition, we also synthesized the dimers of 1-(1H-benzimidazol-1-yl

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