71480-85-8

Usage

Molecular weight

164.21 g/mol

Derivative of

Acetohydrazide

Functional groups

Methylphenylamino group attached to the acetyl group

Common uses

Synthesis of pharmaceutical and agrochemical products, research and development

Biological activities

Various biological activities

Potential applications

Medicine, agriculture.

Upstream product

• 21911-74-0 (methyl-phenyl-amino)-acetic acid ethyl ester 
• 20059-60-3 N-methyl-N-p-phenylglycine methyl ester 
• 100-61-8 N-methylaniline 

Downstream Products

• 225091-87-2 2-(N-methyl-N-phenylaminomethyl)-1,3,4-oxadiazole 
• 142503-96-6 Methyl-phenyl-(6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-ylmethyl)-amine 
• 142503-95-5 Methyl-phenyl-(6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-ylmethyl)-amine 
• 142503-94-4 5-[(Methyl-phenyl-amino)-methyl]-4-{[1-phenyl-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazole-3-thiol 
• 142503-93-3 3-(N-phenyl-N-methyl)aminomethyl-4-amino-5-mercapto-1,2,4-triazole 
• 225091-88-3 2-(N-methyl-N-(4-iodophenyl)aminomethyl)-1,3,4-oxadiazole 

Relevant academic research and scientific papers

KINASE INHIBITOR

The present invention aims to provide a novel kinase inhibitor and the like, and a therapeutic agent for a disease, a drug discovery screening method and the like utilizing such inhibitor and the like. The compound represented by the following formula (I) and a salt thereof can inhibit plural kinases including LATS (particularly LATS2) which is the major kinase in the Hippo signal transduction pathway. In addition, diseases or tissue damage associated with failure of cellular proliferation can be treated. Therefore, the present invention is beneficial, for example, in the research field of cell functions and diseases, in which the Hippo signal transduction pathway is involved, and the like. Furthermore, it is beneficial in the medical field for the treatment of such diseases and the like. wherein each symbol is as defined in the DESCRIPTION.

ADDITIVE COMPOSITION FOR CULTURE MEDIUM, ADDITIVE COMPOUND FOR CULTURE MEDIUM, AND METHOD FOR CULTURE OF CELLS OR TISSUE USING SAME

The present invention provides a medium additive composition containing a compound represented by the following formula (I), or a salt thereof: {wherein each symbol is as defined in the DESCRIPTION.}

Synthesis of 2-[N-methyl-N-(4-iodo-phenyl)aminomethyl]-1,3,4-oxa- diazole and its use as a protective synthon for indirect iodination of ketosteroids

2-(N-methyl-N-phenylaminomethyl)-1, 3, 4 oxadiazole can readily be iodinated to 2-[N-methy-N-(4 -iodophenyl) aminomethyl] - 1, 3, 4-oxadiazole which in a one-step hydrolysis condensation serves as an indirect prosthetic moiety for iodination / radioiodina

Synthesis, spectral studies and biological activities of some N-bridged heterocycles derived from 3-arylaminomethyl-4-amino-5-mercapto-1,2,4- triazoles

Synthesis of four 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles starting from substituted anilines is described. These triazoles were employed in the synthesis of some N-bridged heterocycles carrying arylaminomethyl substituents. All the newly synthesized compounds were characterized by analytical, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial and antiviral properties.