71485-48-8Relevant academic research and scientific papers
5(4H)-oxazolones as intermediates in the carbodiimide- and cyanamide-promoted peptide activations in aqueous solution
Danger, Grégoire,Michaut, Arthur,Bucchi, Manon,Boiteau, Laurent,Canal, Justine,Plasson, Rapha?l,Pascal, Robert
supporting information, p. 611 - 614 (2013/02/23)
The early days: Although considered a species to be avoided in peptide chemistry, the intermediacy of 5(4H)-oxazolones is demonstrated to be essential for the formation of peptides through cyanamide and carbodiimide activation in aqueous solution (see sch
Peptide Synthesis at High Pressure: Activation Volume of a Peptide Coupling, Synthesis of a Glutathione Derivative
Klaerner, Frank-Gerrit,Kalthof, Ulrike,Gante, Joachim
, p. 359 - 364 (2007/10/03)
From the pressure-induced rate enhancement the activation volume of the peptide coupling 1 with the sodium salt of glycine 2 leading to the corresponding dipeptide derivative 3 was determined to be strongly negative (ΔV≠ = -(19.3 ± 0.5) cm
