7149-44-2

Usage

Uses

Used in Coordination Chemistry:
N-(4-Pyridylmethyl)ethylenediamine is used as a chelating ligand for the formation of stable complexes with metal ions, such as copper and zinc. Its bidentate nature allows for strong binding and coordination, making it a valuable component in the synthesis of metal-organic complexes and coordination polymers.
Used in Catalysis:
In the field of catalysis, N-(4-Pyridylmethyl)ethylenediamine is employed as a ligand in the development of catalytic systems. Its ability to form stable complexes with metal ions contributes to the enhancement of catalytic activity and selectivity in various chemical reactions.
Used in Medicinal Chemistry:
N-(4-Pyridylmethyl)ethylenediamine has been studied for its potential applications in medicinal chemistry. Its metal-complexing properties can be utilized in the design and synthesis of metal-based drugs, which may exhibit unique pharmacological properties and therapeutic effects.
Used in Material Science:
In material science, N-(4-Pyridylmethyl)ethylenediamine is used as a building block for the development of new materials with specific properties. Its ability to form metal-organic complexes and coordination polymers can lead to the creation of materials with tailored characteristics, such as magnetic, optical, or electronic properties, for various applications.
Overall, N-(4-Pyridylmethyl)ethylenediamine is a versatile compound with a wide range of applications in chemical research and development, particularly in coordination chemistry, catalysis, medicinal chemistry, and material science. Its unique properties and potential for forming stable metal complexes make it a valuable asset in the advancement of these fields.

InChI:InChI=1/C8H13N3/c9-3-6-11-7-8-1-4-10-5-2-8/h1-2,4-5,11H,3,6-7,9H2

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 107-15-3 ethylenediamine 

Relevant academic research and scientific papers

Fluorescent probe for tumor diagnosis and treatment as well as preparation method and application of fluorescent probe

The invention provides a fluorescent probe for tumor diagnosis and treatment as well as a preparation method and an application of the fluorescent probe. In the fluorescent probe, an azacyclo structure base is taken as an H receptor, a near infrared fluorescent dye with high extinction coefficient and tumor targeting effect is taken as a fluorophore, then the OFF-ON type probe capable of regulating fluorescence intensity by rapid PET (photoinduced electron transfer) process is formed, fluorescence of the probe is strengthened in a slightly acidic environment of tumor, tumor detection is realized, the probe has strong PA (photoacoustic) signals at the tumor while fluorescence imaging is performed, and tumor boundary can be determined accurately by NIRF/PA bimodal imaging. The fluorescentprobe also has good photo-thermal treatment effect on the tumor and can be used for preparing corresponding tumor treatment drugs.

In response to a pH of restoring near-infrared fluorescence probe and its preparation method and application

The invention provides a restoring-type near infrared fluorescence probe with pH response. The chemical structural formula is shown as a formula (I) in the specification, wherein X refers to C(CH3)2, O, S or Se, Y refers to halogen, Z refers to NH, O or S, R1 and R2 are respectively independently selected from H, C1-18 alkyl or SO3R5, R5 refers to C1-18 alkyl or benzyl, and R3 and R4 are respectively independently selected from C1-18 alkyl or benzyl. When the restoring-type near infrared fluorescence probe with pH response is between pH 5.0 and pH 7.5, the fluorescence intensity is gradually enhanced along with reduction of the pH value, and an excellent linear relation is formed between the fluorescence intensity and the pH value. The stocks displacement is large, the signal to noise ratio is low, the toxicity is low, the damage to cells and living bodies is small, the pKa is 6.4, the probe is very suitable for tumor detection, and the defects of fluorescence probes in the prior art are overcome. The invention also provides a method for preparing the probe. The preparation method is simple.

Design, synthesis, and evaluation of unsymmetrical difluoro-boron complexes with imidazoline as potential fungicides

A series of unsymmetrical difluoroboron (BF2) complexes with pyridine and imidazoline were synthesized by reaction of new chelating ligands (arylmethyl-imidazolidinylidene)-pyridin-2-yl-amine with boron trifluoride diethyl etherate. All the ligands and BF2 complexes were structurally characterized by IR, HRMS, 1H, 13C, 11B, and 19F NMR,indicating the bidentate complexation of imidazoline nitrogen and the pyridine nitrogen to the boron center. Evaluation of agricultural bioactivities showed that some of the BF2 complexes exhibited moderate fungicidal activities, and most of the BF2 complexes exhibited higher activities than the none-BF2 complexed substrates.

KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS

The present invention provides ketolide derivatives, which can be used as antibacterial agents. In particular, compounds described herein can be used for treating or preventing conditions caused by or contributed to by Gram-positive, Gram-negative or anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus or Enterobactericeae. Also provided are processes for preparing siuch ketolide derivatives, pharmaceutical compositions thereof, and methods of treating bacterial infections.

Imidazolidinones as brain activators

This invention relates to imidazolidinone compounds of the formula STR1 wherein Q is methylene group or a single bond: R is a heterocyclic group selected from the group consisting of pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl and 1,3-thiazolyl which may be unsubstituted or with a substituent selected from the group consisting of lower alkyl, lower alkoxy and halogen atom, wherein R is bonded to Q or, when Q is a single bond, to the imidazolidinone ring, through the carbon atom of R; the ring A is an unsubstituted phenyl or a substituted phenyl having 1 or 2 substituent(s) selected from the group consisting of lower alkyl, lower alkoxy, halogen, lower alkylthio, trihalogeno-lower alkyl and nitro; Y is vinylene group or ethynylene; m is a integer from 1 to 6 and n is 0, 1 or 2, or a pharmacetically acceptable salt thereof. These compounds aer useful as cerebral activators, anti-depressants and nootropic drugs.

Pesticidal novel nitromethylene derivatives

A pesticidal nitromethylene derivative of the formula STR1 in which R is a hydrogen atom or a lower alkyl group, m is 2, 3 or 4, and n is 0, 1, 2 or 3, is produced by reacting a compound of the formula STR2 in which R' each independently is a lower alkyl group, or together are an alkylene group forming a ring with the adjoining sulfur atoms.