714951-44-7

Upstream product

• 1254709-10-8 (4R,5S)-tert-butyl 3,4-bis(4-methoxyphenyl)-2-oxooxazolidine-5-carboxylate 
• 714951-38-9 tert-butyl (R,R,R)-2-hydroxy-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-(4'-methoxyphenyl)propanoate 
• 714951-42-5 tert-butyl (2R,3R)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-(4-methoxyphenyl)propanoate 
• 714951-39-0 tert-butyl (2R,3R)-3-amino-2-hydroxy-3-(4-methoxyphenyl)propanoate 
• 53484-52-9 tert-butyl (E)-3-(4-methoxyphenyl)prop-2-enoate 
• 714951-43-6 tert-butyl (2R,3R)-3-[(tert-butoxycarbonyl)amino]-2-(mesyloxy)-3-(4-methoxyphenyl)propanoate 

Downstream Products

• 220736-25-4 (4R,5S)-5-(hydroxymethyl)-4-(4-methoxyphenyl)-1,3-oxazolidin-2-one 

Relevant academic research and scientific papers

A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral Bronsted acid-Rh2(OAc)4 Co-catalyzed enantioselective three-component reactions

A new approach to synthesize optically active β-amino-α-hydroxyl acid derivatives via chiral Bronsted acid-Rh2(OAc) 4 cocatalyzed three-component reactions of diazo acetates with alcohols and imines is reported. A matched reaction sy

Asymmetric synthesis of (4R,5R)-cytoxazone and (4R,5S)-epi-cytoxazone.

(4R,5R)-Cytoxazone has been prepared in four steps and in 61% overall yield and >98% ee. Conjugate addition of lithium (R)-N-benzyl-N-[small alpha]-methylbenzylamide to tert-butyl (E)-3-(p-methoxyphenyl)prop-2-enoate and subsequent in situ diastereoselect