714951-39-0

Upstream product

• 53484-52-9 tert-butyl (E)-3-(4-methoxyphenyl)prop-2-enoate 

Downstream Products

• 714951-43-6 tert-butyl (2R,3R)-3-[(tert-butoxycarbonyl)amino]-2-(mesyloxy)-3-(4-methoxyphenyl)propanoate 
• 714951-44-7 tert-butyl (4R,5S)-4-(4-methoxyphenyl)-2-oxo-1,3-oxazolidine-5-carboxylate 
• 691410-75-0 (4R,5R)-4-(4-methoxyphenyl)-1,3-oxazolidine-2-one-5-carboxylic acid 
• 220736-25-4 (4R,5S)-5-(hydroxymethyl)-4-(4-methoxyphenyl)-1,3-oxazolidin-2-one 
• 220736-25-4 (4R,5R)-cytoxazone 
• 714951-40-3 tert-butyl (4R,5R)-4-(4-methoxyphenyl)-2-oxo-1,3-oxazolidine-5-carboxylate 

Relevant academic research and scientific papers

Asymmetric synthesis of (4R,5R)-cytoxazone and (4R,5S)-epi-cytoxazone.

(4R,5R)-Cytoxazone has been prepared in four steps and in 61% overall yield and >98% ee. Conjugate addition of lithium (R)-N-benzyl-N-[small alpha]-methylbenzylamide to tert-butyl (E)-3-(p-methoxyphenyl)prop-2-enoate and subsequent in situ diastereoselect