714959-64-5Relevant academic research and scientific papers
High turnover frequency observed in catalytic enantioselective additions of enecarbamates and enamides to iminophosphonates
Kiyohara, Hiroshi,Matsubara, Ryosuke,Kobayashi, Shu
, p. 5333 - 5335 (2006)
In addition reactions of enecarbamates and enamides, extremely high turnover frequency of the catalyst was observed in comparison with that of silicon enolate addition reactions. This is presumably due to fast transfer of the proton that locates on the nu
PROCESS FOR PRODUCING AMINOPHOSPHONIC ACID DERIVATIVE
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Page/Page column 5; 8; 10, (2008/06/13)
To present a reaction system that efficiently catalyzes an enantio selective asymmetric nucleophilic addition reaction of an ±-iminophosphonic acid ester. An optically active ±-amino-3-oxophosphonic acid derivative is produced through an asymmetric addition reaction of an ±-iminophosphonic acid ester and a nucleophilic agent (for example, a silyl enol ether).
Catalytic asymmetric synthesis of α-amino phosphonates using enantioselective carbon-carbon bond-forming reactions
Kobayashi, Shu,Kiyohara, Hiroshi,Nakamura, Yoshitaka,Matsubara, Ryosuke
, p. 6558 - 6559 (2007/10/03)
We have developed highly enantioselelctive reactions of silicon enolates with N-acyl-α-iminophosphonates leading to optically active α-amino phophonates. A copper (II)-diamine complex was shown to be effective in this reaction, and high levels of yield an
