71530-58-0

Usage

Uses

Used in Organic Synthesis:
3-Isopropyl benzene sulfonyl chloride is used as a reagent in organic synthesis for the introduction of the tosyl group, which acts as a leaving group in nucleophilic substitution reactions. This allows for the formation of new chemical bonds and the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Isopropyl benzene sulfonyl chloride is used as a protecting group for alcohols and amines. This helps to prevent unwanted reactions during the synthesis of complex molecules, ensuring the desired product is obtained.
Used in Production of Dyes, Pigments, and Plastics:
3-Isopropyl benzene sulfonyl chloride is utilized in the production of dyes, pigments, and plastics, contributing to the development of various colorants and materials used in different industries.
Safety Precautions:
Due to its corrosive nature, 3-Isopropyl benzene sulfonyl chloride should be handled and stored with care. It can cause skin and eye irritation, as well as respiratory issues when inhaled. Proper protective equipment, such as gloves, goggles, and respiratory masks, should be worn during handling to minimize the risk of exposure.

Upstream product

• 98-82-8 Isopropylbenzene 

Downstream Products

• 1272718-38-3 N-[2-iodo-4-(trifluoromethyl)-phenyl]-3-(1-methylethyl)benzenesulfonamide 
• 1272718-39-4 4-[(RS)-hydroxy[1-[[3-(1-methylethyl)phenyl]sulfonyl]-5-(trifluoro-methyl)-1H-indol-2-yl]methyl]benzoic acid, methyl ester 
• 1272718-40-7 4-[[1-[[3-(1-methylethyl)phenyl]sulfonyl]-5-(trifluoromethyl)-1H-indol-2-yl]methyl]benzoic acid, methyl ester 
• 1203588-21-9 1-[[3-(1-methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indole-2-pentanoic acid 1,1-dimethylethyl ester 
• 1203588-08-2 1-[[3-(1-methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indole-2-butanoic acid methyl ester 
• 1203588-12-8 1-[[3-(1-methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indole-2-butanoic acid tris(hydroxymethyl)aminomethane salt 
• 1203588-11-7 1-[[3-(1-methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indole-2-butanoic acid piperazine salt 
• 1203588-10-6 1-[[3-(1-methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indole-2-butanoic acid sodium salt 
• 1203588-09-3 1-[[3-(1-Methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indole-2-butanoic acid 
• 1203588-07-1 6-[2-(((3-(1-Methylethyl)phenyl)sulphonyl)amino]-5-(trifluoro-methyl)phenyl]-5-hexynoic acid, methyl ester 

Relevant academic research and scientific papers

SULFONATION OF CUMENE WITH SULFURIC AND HALOGENOSULFONIC ACIDS

The sulfonation of cumene by sulfuric and chloro- and fluorosulfonic acids in the range of 0-100 deg C under heterogenous and heterogenous-homogenous conditions gives mixtures of isomeric sulfonyl halides and/or sulfonic acids, in which the para isomer predominates (90-95percent of the total isomers at temperatures above 75 deg C and/or with the addition of the sulfonating agent to the cumene).If the reagents are mixed in the opposite order and at low temperatures (0-25 deg C), the proportion of the ortho isomer in the mixture of sulfo products increases to 20-22percent.The yield of the sulfonyl halides show an extremal relationship with temperature.The composition of the sulfonic acids and their halides formed under the conditions of a single experiment with the halogenosulfonic acids differ as a result, probably, of the nonequilibrium nature of the process and of the presence of several paths to the formation of the acid halides.