7154-01-0

Basic information

• Product Name: Safrolglycol
• Synonyms: Safrolglycol;2',3'-Dihydro-2',3'-dihydroxysafrole;3-(3,4-Methylenedioxyphenyl)-1,2-propanediol;NSC 43297;3-(Benzo[d][1,3]dioxol-5-yl)propane-1,2-diol
• CAS NO: 7154-01-0
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.19988
• Mol File: 7154-01-0.mol

Chemical Properties

• Melting Point: 69 °C
• Boiling Point: 392.5°Cat760mmHg
• Flash Point: 191.2°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 7.28E-07mmHg at 25°C
• Refractive Index: 1.598
• PKA: 14.12±0.20(Predicted)
• CAS DataBase Reference: Safrolglycol(CAS DataBase Reference)
• NIST Chemistry Reference: Safrolglycol(7154-01-0)
• EPA Substance Registry System: Safrolglycol(7154-01-0)

Safety Data

• Hazardous Substances Data: 7154-01-0(Hazardous Substances Data)

Usage

Uses

Used in Perfumery and Fragrance Industry:
Safrolglycol is used as a fragrance ingredient for its distinctive floral, sweet, and spicy scent. It is incorporated into a wide range of personal care products such as soaps, lotions, and cosmetics to provide a pleasant and long-lasting aroma.
Used in Industrial Applications:
Due to its solvent properties, Safrolglycol is utilized in various industrial processes. It can be employed as a solvent in the manufacturing of certain products, helping to dissolve and mix components effectively, thereby enhancing the production process and end-product quality.

InChI:InChI=1/C10H12O4/c11-5-8(12)3-7-1-2-9-10(4-7)14-6-13-9/h1-2,4,8,11-12H,3,5-6H2

Upstream product

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Downstream Products

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Relevant articles and documents

Site-Selective Mono-Oxidation of 1,2-Bis(boronates)

Site-selective oxidation of vicinal bis(boronates) is accomplished through the use of trimethylamine N-oxide in 1-butanol solvent. The reaction occurs with good efficiency and selectivity across a range of substrates, providing 2-hydro-1-boronic esters which are shown to be versatile intermediates in the synthesis of chiral building blocks.

Modular synthesis and biological investigation of 5-hydroxymethyl dibenzyl butyrolactones and related lignans

Dibenzyl butyrolactone lignans are well known for their excellent biological properties, particularly for their notable anti-proliferative activities. Herein we report a novel, efficient, convergent synthesis of dibenzyl butyrolactone lignans utilizing the acyl-Claisen rearrangement to stereoselectively prepare a key intermediate. The reported synthetic route enables the modification of these lignans to give rise to 5-hydroxymethyl derivatives of these lignans. The biological activities of these analogues were assessed, with derivatives showing an excellent cytotoxic profile which resulted in programmed cell death of Jurkat T-leukemia cells with less than 2% of the incubated cells entering a necrotic cell death pathway.

LITHIATION OF THE BENZENE RING IN THE PRESENCE OF ortho-ALKYL SUBSTITUENTS BEARING ONE OR TWO HETEROATOMS ON THE β-CARBON. A CONVENIENT SYNTHESIS OF MELLEIN AND KIGELIN

The title reaction can be successfully accomplished by proton-metal exchange with n-butyllithium, and the usually observed elimination to a styrene derivative suppressed, provided an appropriate combination of heteroatoms bound to the β-carbon of the alky