71545-60-3

Usage

Uses

Used in Pharmaceutical Synthesis:
ETHYL 2,2-DIMETHOXYETHYLCARBAMATE is used as a precursor in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
ETHYL 2,2-DIMETHOXYETHYLCARBAMATE is also utilized in the production of agrochemicals, playing a role in the creation of substances that help protect crops and enhance agricultural productivity.
Used as a Protecting Group in Organic Synthesis:
ETHYL 2,2-DIMETHOXYETHYLCARBAMATE serves as a protecting group for amines and amino acids in organic synthesis, which is crucial for preserving the integrity of these molecules during chemical reactions.
Used in Chemical Industry as a Reagent:
It is employed as a reagent in the synthesis of new chemical compounds, facilitating the creation of innovative materials and substances.
Used in Advanced Material Production:
ETHYL 2,2-DIMETHOXYETHYLCARBAMATE acts as a building block for the production of advanced materials, contributing to the development of cutting-edge technologies and products.
Safety Precautions:
It is important to handle ETHYL 2,2-DIMETHOXYETHYLCARBAMATE with care, as it can be harmful if swallowed or inhaled and may cause irritation to the skin and eyes. Proper safety measures should be taken during its use and storage.

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 22483-09-6 2,2-dimethoxyethylamine 
• 343333-20-0 C₇H₁₁Cl₂NO₄ 

Downstream Products

• 128740-02-3 ethyl N-(2,2-dimethoxyethyl)-N-(prop-2-en-1-yl)carbamate 
• 128740-03-4 N-allyl-N-(2-oxoethyl)carbamic acid,ethyl ester 
• 370879-99-5 ethyl (3aR,6aR)-1-[(1R)-1-phenylethyl]-2,3,3a,4,6,6a-hexahydro-pyrrolo[3,2-c]pyrrole-5-carboxylate 
• 132414-78-9 ethyl 1-benzyl-octahydropyrrolo[2,3-c]pyrrole-5-carboxylate 
• 132414-77-8 ethyl but-3-en-2-yl(2-oxoethyl)carbamate 
• 132415-01-1 ethyl 1-benzyl-3a-fluorohexahydropyrrolo[2,3-c]pyrrole-5(1H)-carboxylate 
• 132414-75-6 ethyl (2-fluoroallyl)(2-oxoethyl)carbamate 

Relevant academic research and scientific papers

1-(5-(2-CYANOPYRIDIN-4-YL)OXAZOLE-2-CARBONYL)-4-METHYLHEXAHYDROPYRROLO[3,4-B]PYRROLE-5(1H)-CARBONITRILE AS A USP30 INHIBITOR FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION, CANCER AND FIBROSIS

The present invention relates to hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carbonitriles with activity as inhibitors of the deubiquitylating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunctio

DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A BICYCLO MOIETY

The disclosure provides compounds having formula (I), wherein the substituents are as defined herein. The compounds are useful for modulating the dopamine D3 receptor and for treating conditions associated therewith, such as addictions, drug dependency, and psychiatric conditions.

2 - (2, 4, 5 - SUBSTITUTED -ANILINO) PYRIMIDINE DERIVATIVES AS EGFR MODULATORS USEFUL FOR TREATING CANCER

The present invention relates to certain 2-(2,4,5-substituted-anilino) pyrimidine compounds and pharmaceutically acceptable salts thereof which may be useful in the treatment or prevention of a disease or medical condition mediated through certain mutated forms of epidermal growth factor receptor (for example the L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant). Such compounds and salts thereof may be useful in the treatment or prevention of a number of different cancers. The invention also relates to pharmaceutical compositions comprising said compounds and salts thereof, especially useful polymorphic forms of these compounds and salts, intermediates useful in the manufacture of said compounds and to methods of treatment of diseases mediated by various different forms of EGFR using said compounds and salts thereof.

The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists

The 5-HT2C receptor has been implicated in the regulation of appetite. As such, small molecule agonists to this receptor may serve as novel therapies to combat obesity. We describe here the identification, synthesis, and SAR of a 5-HT2C/s

Pharmaceutically active compounds

Compounds of formula (I) wherein: R1 and R19 independently represent hydrogen, alkyl C1-6, alkoxy C1-6, alkylthio C1-6, halogen, hydroxyl or amino; R2 represents H or alkyl; R3 represents phenyl, a 6-membered heterocyclic aromatic ring containing one or two nitrogen atoms, or a 5-membered heterocyclic aromatic ring containing 1 to 3 heteroatoms selected from O,N, and S, which phenyl or heterocyclic aromatic ring may be optionally substituted by alkyl C1-6, alkoxy C1-6, haologen, hydroxyl, alkylthio C1-6, cyano, trifluoromethyl, nitro, hydroxymethyl, amino, a group --(CH2)c NHCO2 R10, a group --(CH2)c NR5 R6, or a group --CO2 R11 ; or R3 represents hydrogen or alkyl C1-8, which alkyl group may be optionally substituted by amino or a group --NHCO2 R10 ; R4 represents hydrogen or alkyl C1-6; or R3 and R4 taken together represent a group (CH2)a Z(CH2)b ; c represents an integer 0 to 2; and pharmaceutically acceptable salts thereof, have been found to be useful as a pharmaceuticals. The compounds may especially be used in the treatment of inflammatory disorders.

2,7-Diazabicyclo[3.3.0]octanes as novel h5-HT(1D) receptor agonists

The conformational restriction of a (benzylamino)methyl substituted pyrrolidine to form 2,7-diazabicyclo[3.3.0]octanes has led to a series of compounds with high affinity at the h5-HT(1D) receptor as well as dramatically increased concentrations in the hepatic portal vein following oral administration.

7-(1-PYRROLIDINYL)-3-QUINOLONE-AND-NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS AND FEED ADDITIVES

7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives, of the formula in which X1 is halogen, X2 is hydrogen, halogen, amino or other radical, R1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical, R2 is hydrogen, alkyl or a dioxolylmethyl radical, R 3 i s A is N, CH, C-halogen, or the like, or forms a bridge with R1, and addition products thereof