7162-59-6

Usage

Uses

Used in Fragrance Industry:
2-N-HEXYLOXYBENZALDEHYDE is used as a scenting agent for its distinctive sweet, floral, and woody aroma, contributing to the creation of various perfumes, cosmetics, and personal care products.
Used in Chemical Manufacturing:
2-N-HEXYLOXYBENZALDEHYDE serves as a building block in the synthesis of other chemicals, expanding its utility beyond the fragrance sector.
Used in Food Industry:
As a flavoring agent, 2-N-HEXYLOXYBENZALDEHYDE enhances the taste profiles of food products, adding depth and complexity to their flavor profiles.
The synthesis of 2-N-HEXYLOXYBENZALDEHYDE is typically achieved through the chemical reaction of hexyl alcohol and salicylaldehyde, and its application is subject to safety and environmental regulations to ensure responsible handling and disposal.

InChI:InChI=1/C13H18O2/c1-2-3-4-7-10-15-13-9-6-5-8-12(13)11-14/h5-6,8-9,11H,2-4,7,10H2,1H3

Upstream product

• 111-25-1 1-bromo-hexane 
• 90-02-8 salicylaldehyde 
• 3351-71-1 [2-(hexyloxy)phenyl]methanol 

Downstream Products

• 3351-71-1 [2-(hexyloxy)phenyl]methanol 
• 104090-76-8 2-(hexyloxy)benzothiomorpholide 
• 13736-63-5 2-hexyloxy-5-nitrobenzaldehyde 
• 1448644-27-6 o-HOPF 

Relevant academic research and scientific papers

Multicolor Fluorescent Polymers Inspired from Green Fluorescent Protein

Mimicking the green fluorescent protein (GFP), multicolor fluorescent polymers possessing enhanced fluorescence have been developed and applied to single-excitation cell imaging. The GFP core chromophore was covalently linked to the azide-functionalized a

Synthesis and characterization of novel soluble fulleropyrrolidine derivatives and their photovoltaic performance

Currently, [60] fullerene derivatives are the focus of considerable research due to their important roles in many fields, especially material science. In this study, we synthesized the following two novel fulleropyrrolidine derivatives: C60-fused N-methyl-(4-hexyloxybenzen- 2-yl) pyrrolidine, (p-HOPF) and C60-fused N-methyl-(2-hexyloxybenzen- 2-yl) pyrrolidine, (o-HOPF). Structural assignments of the two fullerene derivatives were made through 1H NMR and FAB-MS. We also measured the optical and electrochemical properties of p-HOPF and o-HOPF through UV/Vis spectrophotometry and cyclic voltammetry. We found that the difference in the position of the alkoxyl substituent on the phenyl ring greatly affects the characteristics of the molecules. In particular, from the 1H NMR spectrum, we found that the hydrogen atoms on the carbons adjacent to the oxygens in p-HOPF and o-HOPF have completely different chemical environments. In order to study the effects of the substituent group positions on photovoltaic performance, photovoltaic devices were fabricated. The highest power conversion efficiency, 0.71%, was achieved when using o-HOPF as the electron acceptor. Copyright

Synthesis of N-arylpyridinium salts bearing a nitrone spin trap as potential mitochondria-targeted antioxidants

The generation of excess reactive oxygen species (ROS) in mitochondria is responsible for much of the oxidative stress associated with ageing (aging), and mitochondrial dysfunction is part of the pathology of neurodegeneration and type 2 diabetes. Lipophilic pyridinium ions are known to accumulate in mitochondria and this paper describes a general route for the preparation of nitrone-containing N-arylpyridinium salts having a range of lipophilicities, as potential therapeutic antioxidants. The compatibility of nitrones with the Zincke reaction is the key to their synthesis. Their trapping of carbon-centred radicals and the EPR spectra of the resulting nitroxides are reported.

Expedient synthesis and solvent dependent oxidation behavior of a water-soluble IBX derivative

IBX derivative 6, synthesized in two steps from 2-aminoterephthalic acid, 8, is soluble in both DMF and water. A variety of alcohols are oxidized using 6 in DMF with ease and selectivity identical to that of parent IBX. However, oxidations carried out in water and other aqueous solvent mixtures using 6 exhibit unique selectivities toward different substrates and provide products different from reactions carried out in DMF. A mechanistic rationale is provided for this solvent dependent behavior of 6.

Quantitative structure-activity relationships of 2,4-diamino-5-(2-X- benzyl)pyrimidines versus bacterial and avian dihydrofolate reductase

Quantitative structure-activity relationships (QSAR) have been formulated for a set of 15 2,4-diamino-5-(2-X-benzyl)pyrimidines versus dihydrofolate reductase from Lactobacillus casei and chicken liver. QSARs were also developed for comprehensive data sets containing mono-, di-, and trisubstituted benzyl derivatives. Particular emphasis was placed on the role played by ortho substituents in the overall binding process and subsequent inhibition of the catalytic process in both the prokaryotic and eucaryotic DHFRs. Comparisons between the two QSARs reveal subtle differences at specific positions which can be optimized to design more selective antibacterial agents.

Productivity in synthesis: A mixture protocol to raise compound output is demonstrated for asymmetric cyclopropanation of allyl alcohols

The productivity of conventional chemical reactions can be improved in favourable cases by using a mixture protocol. This concept is demonstrated for the asymmetric cyclopropanation of 3-arylprop-2-en-1-ols. Mixtures of three or four starting materials give products which are separated by flash chromatography. The enantiomeric excess and yield of each pure compound is comparable to that obtained in conventional single-substrate reactions, leading to an overall efficiency gain, especially in experimentalist effort, and reduced hazard.

Propanamine derivatives

Substituted propanamines having anticoagulant or antifungal activity are disclosed. Also disclosed are methods of use involving the substituted propanamines as well as pharmaceutical compositions containing them.

Substituted 1,3,4-Thiadiazoles with Anticonvulsant Activity. 2. Aminoalkyl Derivatives

This paper describes the synthesis and pharmacological evaluation of a number of substituted 1,3,4-thiadiazoles.The first member of the series, 2-(aminomethyl)-5-(2-biphenylyl)-1,3,4-thiadiazole (7) was found to possess potent anticonvulsant properties in rats and mice and compared favorably with the standard anticonvulsant drugs phenytoin, phenobarbital, and carbamazepine in a number of test situations.The potency of compound 7 was maintained on alkylation of the side-chain nitrogen atom; however, aryl substitution or chain lengthening caused a drop in potency.Replacement of the 2-biphenylyl group by phenyl or benzyl also lead to inactive compounds.