71634-82-7Relevant academic research and scientific papers
Antimicrobial activity of 3-O-Acyl-(-)-epicatechin and 3-O-Acyl-(+)- catechin derivatives
Park, Ki Duk,Park, Yoon Sun,Cho, Sung Jin,Sun, Won Suck,Kim, Sung Han,Jung, Do Hyun,Kim, Jung Han
, p. 272 - 276 (2004)
As an exploratory investigation of antimicrobial promoting compounds, 3-O-acyl-(-)-epicatechins and 3-O-acyl-(+)-catechins possessing various aromatic groups and aliphatic chains of varying length from C4 to C16 for increasing lipophilicity were synthesiz
Inhibitory effects of 3-O-acyl-(+)-catechins on Epstein-Barr virus activation
Uesato, Shinichi,Taniuchi, Keisuke,Kumagai, Ayako,Nagaoka, Yasuo,Seto, Ryota,Hara, Yukihiko,Tokuda, Harukuni,Nishino, Hoyoku
, p. 1448 - 1450 (2003)
In the course of an exploratory investigation of antitumor-promoting catechins, 3-O-acyl-(+)-catechins of varying carbon lengths from C4 to C18 were assessed for inhibitory effects on the activation of the Epstein-Barr virus early an
Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis
Matsubara, Kiminori,Saito, Akiko,Tanaka, Akira,Nakajima, Noriyuki,Akagi, Reiko,Mori, Masaharu,Mizushina, Yoshiyuki
, p. 1578 - 1585 (2008/02/02)
Anti-cancer and anti-angiogenesis effects of green tea catechins have been demonstrated. It has been found that chemical modification of tea catechins improves their biological activities. We examined the chemical modification of epicatechin enhanced anti
Cerium(III) chloride-promoted chemoselective esterification of phenolic alcohols
Torregiani, Elisabetta,Seu, Gianfranco,Minassi, Alberto,Appendino, Giovanni
, p. 2193 - 2196 (2007/10/03)
A mild and operationally simple method for the chemoselective esterification of phenolic alcohols is described. The reaction overcomes the tyranny of protection, and capitalizes on the activation of acyl halides with cerium(III) chloride to selectively esterify alcohol hydroxyls in the presence of phenolic ones. The generality of the reaction was demonstrated with a series of phenolic alcohols of dietary relevance (vanillol, hydroxytyrosol, epicatechin), providing an expeditious entry into a series of compounds of relevance for biomedical research, some of which previously available only by enzymatic methods.
ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE
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Page/Page column 20, (2008/06/13)
A catechin is modified in at least one position (most preferably in the 3-position of the C-ring) to increase its lipophilicity. Contemplated catechins are demonstrated to have significantly improved antibacterial properties, likely due to catastrophic membrane damage.
Anticancer activity of 3-O-acyl and alkyl-(-)-epicatechin derivatives
Park, Ki Duk,Lee, Sul Gi,Kim, Sung Uk,Kim, Sung Han,Sun, Won Suck,Cho, Sung Jin,Jeong, Do Hyeon
, p. 5189 - 5192 (2007/10/03)
We report the synthesis and anticancer effects of 3-O-acyl and alkyl-(-)-epicatechin derivatives.
