716360-63-3Relevant academic research and scientific papers
Biological and structural characterization of rotamers of C-C chemokine receptor type 5 (CCR5) inhibitor GSK214096
Kazmierski, Wieslaw M.,Danehower, Susan,Duan, Maosheng,Ferris, Robert G.,Elitzin, Vassil,Minick, Douglas,Sharp, Matthew,Stewart, Eugene,Villeneuve, Manon
, p. 1296 - 1299 (2014)
We recently reported the discovery of preclinical CCR5 inhibitor GSK214096, 1 (J. Med. Chem. 2011, 54, 756). Detailed characterization of 1 revealed that it exists as a mixture of four separable atropisomers A-D. The two slow-interconverting pairs of rota
