716369-07-2

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 716369-03-8 (2S)-(2-bromo-benzoylamino)-3-hydroxy-propionic acid methyl ester 
• 7154-66-7 2-bromobenzoic acid chloride 

Downstream Products

• 716369-11-8 2-bromo-N-[1-(tert-butyl-dimethyl-silanyloxymethyl)-(2R)-hydroxy-ethyl]-benzamide 
• 716369-15-2 (4R)-(tert-butyl-dimethyl-silanyloxymethyl)-2-[2-(3-phenyl-allylselanyl)-phenyl]-4,5-dihydro-oxazole 
• 716369-21-0 {2-[2-(3-phenyl-allylselanyl)-phenyl]-4,5-dihydro-oxazol-(4S)-yl}-methanol 
• 716369-19-6 2-(2-bromo-phenyl)-(4R)-(tert-butyl-dimethyl-silanyloxymethyl)-4,5-dihydro-oxazole 
• 104713-12-4 (1S)-1-phenylprop-2-en-1-ol 
• 104713-12-4 (R)-1-phenylprop-2-en-1-ol 

Relevant academic research and scientific papers

Vanadium-catalyzed selenide oxidation with in situ [2,3] sigmatropic rearrangement (SOS reaction): Scope and asymmetric applications

A vanadium-catalyzed method for the oxidation of prochiral aryl, allylic selenides with tandem sigmatropic rearrangement has been developed. This protocol has been screened on a series of substrates to test for its generality and effectiveness. The applicability of this methodology to the synthesis of enantiomerically enriched allylic alcohols has been studied on a series of chiral oxazole-containing systems with a diastereomeric ratio (d.r.) of up to 85 : 15. The chiral transfer observed in the allyl alcohol products is the result of a net 1,9- and/or 1,10-induction. Finally, the first example of a selenium-oxygen nonbonding interaction in oxazole-containing selenide appears to have been observed via X-ray crystal analysis.