71663-73-5Relevant academic research and scientific papers
A new synthesis of didehydroamino acid esters
Groundwater, Paul W.,Sharif, Toqir,Arany, Andrea,Hibbs, David E.,Hursthouse, Michael B.,Nyerges, Miklos
, p. 1433 - 1436 (2007/10/03)
A novel synthesis of didehydroamino acid (DDAA) esters 4 is described, starting from aldimines 1. The mechanism for this reaction involves the cycloaddition of an azomethine ylide 2 to an imine 1, followed by the base-catalysed ring-opening of the imidazolidine intermediate 6. This method has also been extended to the synthesis of DDAA esters 4h-j catalysed by an imine 1a.
54. A New Azepine-Ring Synthesis
Kvita, Vratislav,Sauter, Hanspeter,Rihs, Grety
, p. 457 - 463 (2007/10/02)
A new one-step synthesis of an azepine ring is described.The 2H-pyran-2-one ring of methyl cumalate (8) or cumalaldehyde (2) upon reaction with an 1-aminoacryl derivative, e.g. 1 or 6, is opened with subsequent decarboxylation to give a 1-aminobutadiene d
THE SYNTHESES OF N-FREE α-DEHYDROAMINO ACID ESTERS AND N-ACETYL DEHYDRODIPEPTIDE ESTER FROM N-CARBOXY α-DEHYDROAMINO ACID ANHYDRIDE
Shin, Chung-gi,Yonezawa, Yasuchika,Yoshimura, Juji
, p. 1635 - 1638 (2007/10/02)
N-Carboxy α-dehydroamino acid anhydride, derived from N-benzyloxycarbonyl α-dehydroamino acid (DHA) and thionyl chloride, was found to be very useful for the synthesis of N-free DHA ester by alcoholysis and N-acetyl dehydrodipeptide ester by coupling was
