71701-92-3

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine is used as a building block for the synthesis of more complex molecules in the pharmaceutical industry. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine serves as an intermediate in the production of agrochemicals. Its properties allow for the creation of compounds with pesticidal or herbicidal activities, contributing to crop protection and yield enhancement.
Used in Heterocyclic Compounds Production:
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine is utilized as a key intermediate in the synthesis of heterocyclic compounds. Its presence in these compounds can influence their chemical and biological properties, making it an important component in the development of various chemical entities.
It is crucial to handle 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine with care due to its potential health and environmental risks if not properly managed.

InChI:InChI=1/C6H2BrClF3N/c7-4-1-3(6(9,10)11)2-12-5(4)8/h1-2H

Upstream product

• 76041-73-1 3-bromo-5-(trifluoromethyl)pyridin-2-ol 
• 76041-73-1 3-bromo-5-(trifluoromethyl)pyridin-2(1H)-one 
• 79456-30-7 3-bromo-5-trifluoromethyl-pyridin-2-ylamine 

Downstream Products

• 124432-63-9 3-bromo-2-methoxy-5-(trifluoromethyl)pyridine 
• 934279-60-4 2-chloro-5-(trifluoromethyl)pyridine-3-carbaldehyde 
• 943551-28-8 (2-chloro-5-(trifluoromethyl)pyridin-3-yl)methanol 
• 1026086-96-3 2-chloro-5-(trifluoromethyl)pyridin-3-ylmethane chloride 
• 216766-05-1 3-bromo-2-ethoxy-5-(trifluoromethyl)pyridine 

Relevant academic research and scientific papers

HETEROCYCLIC DERIVATIVES AS CETP INHIBITORS

The present invention provides a compound of formula (I), said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

ORGANIC COMPOUNDS

The present invention provides a compound of formula (I), said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

PYRIDINYL AMINE DERIVATIVES AS INHIBITORS OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP)

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the variables are as defined, useful as inhibitors of chlosteryl ester transfer protein.

2,3,5-TRISUBSTITUTED PYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2

The invention encompasses the novel compound of Formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula (I).

2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2

The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

Chemical compounds

Pesticidal compounds of formula (I) wherein R1, R2, R3 and R4 are independently selected from hydrogen, cyano, halogen, lower alkyl optionally substituted by halogen, lower alkoxy optionally substituted by halogen, lower alkenyl optionally substituted by halogen; amino and mono- or di-(lower alkyl) amino;, R6 is oxygen or sulphur;, R7, R8 and R10 are independently selected from hydrogen, halogen, cyano, lower alkyl optionally substituted by halogen, lower alkoxy optionally substituted by halogen, lower thioalkoxy optionally substituted by halo; and, R9 is lower alkyl substituted by halogen or lower alkenyl optionally substituted by halogen. The preparation of these compounds together with their use in combatting insect, acarine and nemotode pests is also described.

Herbicidal pyridine compounds

Herbicidal 3- and/or 5-halogenomethyl-pyrid-2-yloxyphenoxy compounds and processes for making and using the same. Intermediates for making these compounds and their preparation are also disclosed. Thus, for example, 2-chloro-5-trichloromethylpyridine is prepared by a liquid phase chlorination of 3-methylpyridine under the influence of ultra violet light.