71701-99-0

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-(difluoromethyl)pyridine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique chemical properties make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
2-Chloro-5-(difluoromethyl)pyridine is used as a chemical intermediate in the production of agrochemical compounds, particularly insecticides. Its potential applications in crop protection contribute to the development of effective and innovative pest control solutions.
Used in Medicinal Chemistry:
2-Chloro-5-(difluoromethyl)pyridine is utilized in medicinal chemistry for its potential applications in the discovery and design of novel therapeutic agents. Its unique structure and properties facilitate the exploration of new drug candidates.
Used in Research and Development:
2-Chloro-5-(difluoromethyl)pyridine is employed in research and development settings to explore its chemical properties and potential uses. Its versatility as a chemical intermediate makes it an important tool for advancing scientific knowledge and innovation in various fields.

Upstream product

• 23100-12-1 6-chloronicotinylaldehyde 

Downstream Products

• 947371-16-6 2-({5-[bromo(difluoro)methyl]pyridin-2-yl}oxy)-N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methylpropanamide 

Relevant academic research and scientific papers

Manufacturing method of making heteroarylacetic compd. defluoromethyl

PROBLEM TO BE SOLVED: To provide a method for easily producing a difluoromethyl heteroaryl compound with high yield at low cost. SOLUTION: In the method for producing the difluoro methyl heteroaryl compound, a halogenated heteroaryl compound and a α-silyldifluoro acetate ester compound are reacted with each other in the presence of a metal halogenated compound. COPYRIGHT: (C)2012,JPOandINPIT

PYRIMIDINE PDE10 INHIBITORS

The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

ANTHELMINTIC AGENTS AND THEIR USE

This invention is directed to compounds of the formula (I) and salts therefore that are generally useful as anthelmintic agents or as intermediates in processes for making anthelmintic agents. This invention also is directed to processes for making the co

Discovery of N-{(1S,2S)-2-(3-cyanophenyl)-3-[4-(2-[18F] fluoroethoxy)phenyl]-1-methylpropyl}-2-methyl-2-[(5-methylpyridin-2-yl)oxy] propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use

The discovery of a structurally distinct cannabinoid-1 receptor (CB1R) positron emission tomography tracer is described. Starting from an acyclic amide CB1R inverse agonist (1) as the lead compound, an efficient route to introduce 18F to the mo

RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS

The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.

Herbicidal pyridine compounds

Herbicidal 3- and/or 5-halogenomethyl-pyrid-2-yloxyphenoxy compounds and processes for making and using the same. Intermediates for making these compounds and their preparation are also disclosed. Thus, for example, 2-chloro-5-trichloromethylpyridine is prepared by a liquid phase chlorination of 3-methylpyridine under the influence of ultra violet light.