71756-89-3Relevant academic research and scientific papers
Design synthesis and biological evaluation of novel N-nitro acid amide derivatives as lead compounds of herbicide
Qi, Xiaojuan,Tang, Wenjie,Gao, Shan,Gao, Min,Chen, Changshui,Zhang, Qingye
, (2016/07/26)
A series of N-nitro acid amide derivatives compounds were synthesized based on the active site of target acetohydroxyacid synthase (AHAS, EC: 2.2.1.6) enzyme. All the structures of newly prepared compounds were thoroughly characterized by satisfied IR and 1H NMR spectra. The IC50 values against AHAS enzyme and EC50 values for herbicidal activity against Amaranthus mangostanus L. and Sorghum sudanense of all synthesized target compounds were determined. The compounds II-10, II-21, and II-22 with IC50 values of 7.09 mg/L, 9.07 mg/L, and 9.11 mg/L and the compounds II-8 and II-22 with EC50 values of 9.87 mg/L and 19.88 mg/L against root of Amaranthus mangostanus L. and Sorghum sudanense were illustrated, respectively. Meanwhile, the possible reasons for the lower activity of compounds were analyzed by molecular docking prediction.
N-Nitrourea Derivatives as Novel Potential Fungicides against Rhizoctonia solani: Synthesis, Antifungal Activities, and 3D-QSAR
Cao, Xiufang,Xu, Shengzhen,Li, Xuegang,Shen, Xiaoxia,Zhang, Qingye,Li, Jianhong,Chen, Changshui
experimental part, p. 80 - 88 (2012/08/08)
A series of N-nitrourea derivatives bearing various aryl substituents were conveniently obtained via three steps including nitration, carbamic chlorination, and aminolysis reactions. The structures of all newly synthesized compounds were characterized and confirmed by IR, 1H-NMR, MS, and elemental analysis. The preliminary bioassays indicate that five compounds possess sufficient fungicidal activity against Rhizoctonia solani. Structure-activity relationship (SAR) is also discussed based on the experimental data, and the further quantitative structure-activity relationship (QSAR) was analyzed using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA).
Cycloalkyl substituted N-nitrourea derivatives: A convenient synthesis and biological evaluation
Bai, Zhongyuan,Wei, Zengjun,Wang, Yunchun,Xu, Shengzhen,Li, Xuegang,Chen, Changshui,Cao, Xiufang
experimental part, p. 859 - 868 (2012/05/05)
A series of N-nitrourea derivatives bearing various cycloalkyl were conveniently obtained via three steps including nitration, carbamic chlorination, and aminolysis reactions. The structures of all newly synthesized compounds were elucidated and confirmed
Method for the control of stem growth and stem stiffness of graminaceous crops
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, (2008/06/13)
The invention is a novel method for the control of the relative stem growth of graminaceous crops, comprising applying to the foliage, stems, roots or seeds of said plants, or to the soil in which said plants are grown, a plant growth regulating amount of
