7176-38-7

Basic information

• Product Name: Benzene, 1-(2-nitro-1-propenyl)-4-(phenylmethoxy)-
• CAS NO: 7176-38-7
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol File: 7176-38-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2-nitro-1-propenyl)-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2-nitro-1-propenyl)-4-(phenylmethoxy)-(7176-38-7)
• EPA Substance Registry System: Benzene, 1-(2-nitro-1-propenyl)-4-(phenylmethoxy)-(7176-38-7)

Safety Data

• Hazardous Substances Data: 7176-38-7(Hazardous Substances Data)

Upstream product

• 79-24-3 Nitroethane 
• 4397-53-9 p-benzyloxybenzaldehyde 

Downstream Products

• 7176-39-8 2-(4-benzyloxy-phenyl)-1-methyl-ethylamine 
• 103-86-6 p-hydroxyamphetamine 
• 100780-40-3 Ethyl 3-(p-benzyloxy-phenyl)-4-methylpyrrole-2-carboxylate 

Relevant articles and documents

A Bioinspired Synthesis of Polyfunctional Indoles

Polyfunctional indoles bearing substituents at C5 and C6 are prevalent in natural products, pharmaceuticals, agrochemicals, and materials. Owing to the remoteness of the C5 and C6 positions, indoles of this family can be difficult to prepare, and often require multistep syntheses. Herein, we describe a concise process that converts simple derivatives of tyrosine into 5,6-difunctionalized indoles by direct oxidation of C?H, N?H, and O?H bonds. Our work draws inspiration from the biosynthetic polymerization of tyrosine to make melanin pigments, but makes an important departure to provide well-defined indole heterocycles.