71776-74-4

Usage

InChI:InChI=1/C7H15NO2.ClH/c1-4-5(2)6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t5-,6+;/m1./s1

Upstream product

• 67-56-1 methanol 
• 3054-37-3 DL-isoleucine hydrochloride 
• 73-32-5 DL-isoleucine 
• 319-78-8 isoleucine 

Downstream Products

• 1220697-19-7 C₁₅H₂₁NO₄ 
• 1414492-71-9 methyl (2S,3R)-2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-methylpentanoate 

Relevant academic research and scientific papers

Ligand-Enabled γ-C(sp3)–H Acetoxylation of Triflyl-Protected Amines

A palladium-catalyzed γ-C(sp3)–H acetoxylation of triflyl-protected amines has been achieved. The use of pyridine or 2-alkoxyquinoline-type ligands is key to the success of this transformation. The reaction is highly diastereoselective and easily scalable, and constitutes a direct approach for the synthesis of γ-hydroxy-α-amino acids and β,γ-dihydroxy amines, which are not readily accessible by other routes.

NOVEL HDAC INHIBITORS AND METHODS OF TREATMENT USING THE SAME

Disclosed herein are novel HDAC inhibitors. The HDAC inhibitors may be used in methods of treating cancer. The HDAC inhibitors may be used in methods of treating a neurological disorder.

Highly tunable arylated cinchona alkaloids as bifunctional catalysts

We report the design and evaluation of a library of chiral bifunctional organocatalysts in which the distance between the catalytically active units can be systematically varied.