717878-06-3

Basic information

• Product Name: 1-(4-fluorophenyl)-4-nitro-1H-iMidazole
• Synonyms: 1-(4-fluorophenyl)-4-nitro-1H-iMidazole
• CAS NO: 717878-06-3
• Molecular Formula: C₉H₆FN₃O₂
• Molecular Weight: 207.1612432
• Mol File: 717878-06-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 366.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.29±0.61(Predicted)
• CAS DataBase Reference: 1-(4-fluorophenyl)-4-nitro-1H-iMidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-fluorophenyl)-4-nitro-1H-iMidazole(717878-06-3)
• EPA Substance Registry System: 1-(4-fluorophenyl)-4-nitro-1H-iMidazole(717878-06-3)

Safety Data

• Hazardous Substances Data: 717878-06-3(Hazardous Substances Data)

Usage

Description

1-(4-fluorophenyl)-4-nitro-1H-imidazole is a chemical compound with the molecular formula C9H6FN3O2, belonging to the nitroimidazole class. It features a nitro group and a fluorophenyl group, both of which contribute to its potential biological activity in medicinal chemistry. 1-(4-fluorophenyl)-4-nitro-1H-imidazole is recognized for its antimicrobial and antiprotozoal properties, making it a promising candidate for the development of new drugs to combat microbial infections and parasitic diseases.

Uses

Used in Pharmaceutical Industry:
1-(4-fluorophenyl)-4-nitro-1H-imidazole is used as a chemical intermediate for the development of new drugs due to its antimicrobial and antiprotozoal properties. Its potential application lies in creating medications to treat a variety of microbial infections and parasitic diseases, addressing the need for novel therapeutic options in this area.
Used in Medicinal Chemistry Research:
As a nitroimidazole derivative, 1-(4-fluorophenyl)-4-nitro-1H-imidazole serves as a subject of interest in medicinal chemistry research. Scientists are likely to explore its pharmacological properties, including how it interacts with biological targets and its potential therapeutic uses, to better understand its full range of applications in drug development.
Further research is necessary to fully comprehend the compound's pharmacological properties and its potential therapeutic uses, which could lead to significant advancements in the treatment of various diseases caused by microbial and parasitic pathogens.

Upstream product

• 19182-81-1 1,4-dinitro-1H-imidazole 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

NOVEL COMPOUNDS

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase L1 (UCHL1). The invention further relates to the use of DUB inhibitors in the treatment of cancer and other indications. Compounds of the invention include compounds having the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R8 are as defined herein.

Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds

Spiroindoline urea derivatives, designed to act as NPY Y5 receptor antagonists, were synthesized and their structure-activity relationships were investigated. Of these derivatives, compound 3a showed good Y5 binding affinity with favorable pharmacokinetic