71788-36-8 Usage
Derivative of imidazole
Imidazole is a core structure in the compound.
Thioamide functional group
A硫酰胺 group (-C(=S)NH2) is present in the molecule.
Pharmaceutical synthesis
Used as an intermediate in the synthesis of various pharmaceuticals.
Anti-cancer properties
Potential to inhibit the growth of cancer cells.
Anti-microbial properties
Capable of combating and inhibiting the growth of microorganisms.
Key intermediate
Serves as an important intermediate for the synthesis of other chemical compounds.
Chemotherapy applications
Studied for its potential use in chemotherapy treatment.
Treatment of diseases
Researched for its possible use in treating certain diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 71788-36-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,8 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 71788-36:
(7*7)+(6*1)+(5*7)+(4*8)+(3*8)+(2*3)+(1*6)=158
158 % 10 = 8
So 71788-36-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H8N4S/c1-9-2-8-4(6)3(9)5(7)10/h2H,6H2,1H3,(H2,7,10)
71788-36-8Relevant academic research and scientific papers
Analogs of AICA- and ISOAICA ribosides and their methylated base counterparts
Panzica, Raymond P.,Townsend, Leroy B.
, p. 2345 - 2356 (2007/10/03)
A mild, convenient and efficient synthesis has been developed for imidazole-4-thiocarboxamide and imidazole-5-thiocarboxamide ribosides and the analogous selenocarboxamides. This methodology, i.e., DMF saturated with H2S or H2Se, also converts the corresponding N-methylated bases to the corresponding amides. The imidazole-4(5)-selenocarboxamides were shown to be sensitive to base (pH 11) and were easily converted back to their cyano precursors. The kinetics of these reactions were determined and they indicate that the C5 amides were more reactive than their C4 analogs.
