71814-54-5

Upstream product

• 54289-77-9 3-acetyl-4-hydroxy-1-phenylquinolin-2(1H)-one 
• 685895-25-4 2-oxo-1-phenyl-3-[1-(phenylhydrazono)ethyl]-1,2-dihydroquinolin-4-yl 4-methylbenzenesulfonate 
• 95320-95-9 4-hydroxy-1-phenyl-3-[1-(phenylhydrazono)ethyl]-quinolin-2(1H)-one 

Relevant academic research and scientific papers

Ring closure reactions of 3-arylhydrazonoalkyl-quinolin-2-ones to 1-aryl-pyrazolo[4,3-c]quinolin-2-ones

4-Hydroxy-3-arylhydrazonoalkyl-2-quinolones 6 or reactive derivatives such as 3-arylhydrazonoalkyl-4-tosyloxy-2-quinolones 7 or 4-chloro-3- arylhydrazonoalkyl-2-quinolones 14, which are obtained via 3-acyl-4- hydroxyquinolones 4, 10 or 3-phenylaminomethylene-quinoline-2,4-diones 12, cyclize in excellent yields to 1-aryl-pyrazolo[4,3-c]quinolin-4-ones (11). The cyclization conditions were investigated by differential scanning calorimetry (DSC).