54289-77-9

Usage

InChI:InChI=1/C17H13NO3/c1-11(19)15-16(20)13-9-5-6-10-14(13)18(17(15)21)12-7-3-2-4-8-12/h2-10,21H,1H3

Upstream product

• 122-39-4 diphenylamine 
• 231935-89-0 3-acetyl-4-hydroxy-6-phenylpyrano<3,2-c>quinoline-2,5(6H)-dione 
• 18706-64-4 4-hydroxy-6-phenyl-2H-pyrano<3,2-c>quinoline-2,5(6H)-dione 

Downstream Products

• 14994-75-3 4-hydroxy-1-phenylquinolin-2(1H)-one 
• 161371-37-5 3-acetyl-1-phenyl-4-(4-tosylsulfonyloxy)-1(1H)-quinolone 
• 95320-95-9 4-hydroxy-1-phenyl-3-[1-(phenylhydrazono)ethyl]-quinolin-2(1H)-one 
• 870152-82-2 3-[(2E)-3-(dimethylamino)prop-2-enoyl]-4-hydroxy-1-phenylquinolin-2(1H)-one 
• 1063696-29-6 (2E)-1-(1-phenyl-4-hydroxyquinolin-2(1H)-one-3-yl)-3-(4-chlorophenyl)-2-propen-1-one 
• 1063696-26-3 (2E)-1-(1-phenyl-4-hydroxyquinolin-2(1H)-one-3-yl)-3-(4-methoxyphenyl)-2-propen-1-one 

Relevant academic research and scientific papers

Studies with polyfunctionally substituted heteroarenes: New synthesis of benzo [c] quinolinones and pyrano [3,2-c] quinoline derivatives

Nitration, bromination and acetylation of 4 - hydroxypyranoquinolines 1 yielded 3-nitro-, 3-bromo, and 3-acetylpyranoquinolines 3,5,8. Hyrolysis of 3, 5 and 8 with 2N NaOH afforded 3-nitroacetyl, 3-bromoacetyl and 3- acetylquinolines 4, 6 and 7 respectively. Formylation of 1 or 7 gave 3- formyl pyranoquinolines 9a-c. Reactions of 8 with 2 afforded benzo [c] quinolines 11 and 12. Treatment of 1, 24 or 7 with the ylidene 21 resulted in the formation of pyranoquinolines 25.

Nucleophilic Substitution and Ring Closure Reactions of 4-Chloro-3-nitro-2-quinolones

4-Chloro-3-nitro-2-quinolones 3 obtained from the 4-hydroxy quinolones 1 by nitration and chlorination, reacted with sodium azide to the 4-azido derivatives 4 which cyclized on thermolysis to yield the furoxanes 5.Nucleophilic substitution reactions of 3