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Avermectin B1a aglycone is an acid degradation product that is produced by the hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development, but lacks paralytic activity. Despite its importance as an anthelmintic in animal health, there is limited information on its biological activity or levels in animals or the environment.

71828-14-3

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71828-14-3 Usage

Uses

Used in Animal Health:
Avermectin B1a aglycone is used as an anthelmintic agent for the treatment and control of parasitic nematode infections in animals. It effectively inhibits the development of nematode larvae, helping to reduce the parasite burden and improve the overall health of the animals.
Used in Environmental Studies:
Avermectin B1a aglycone can be used as a research tool in environmental studies to investigate its presence, distribution, and potential impact on ecosystems. Understanding the levels and activity of avermectin aglycone in the environment can help in assessing its ecological risks and informing better management practices.

Check Digit Verification of cas no

The CAS Registry Mumber 71828-14-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,2 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 71828-14:
(7*7)+(6*1)+(5*8)+(4*2)+(3*8)+(2*1)+(1*4)=133
133 % 10 = 3
So 71828-14-3 is a valid CAS Registry Number.

71828-14-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name avermectin B1a aglycone

1.2 Other means of identification

Product number -
Other names avermectin B1a aglycon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71828-14-3 SDS

71828-14-3Downstream Products

71828-14-3Relevant academic research and scientific papers

The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility

Zhang, Changsheng,Albermann, Christoph,Fu, Xun,Thorson, Jon S.

, p. 16420 - 16421 (2006)

The glycosyltransferase AveBI, which is involved in the biosynthesis of the macrolide antihelmintic avermectin (AVM), was characterized in vitro. AveBI was confirmed to catalyze two separate iterative additions of l-oleandrose, and the reversibility of AveBI-catalyzed reaction was also demonstrated. Investigation of sugar nucleotide specificity revealed 10 unique sugar nucleotide substrates which, in combination with five distinct aglycones, led to the production of 50 differentially glycosylated AVM variants. Copyright

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