718599-06-5Relevant academic research and scientific papers
New ring expansion of cyclobutanones: Synthesis of pyrrolinones, pyrrolidines and pyrroles
Verniest, Guido,Boterberg, Stefaan,Bombeke, Filip,Stevens, Christian V.,De Kimpe, Norbert
, p. 1059 - 1063 (2004)
2,2-Dichlorocyclobutanones reacted with various amines to give ring opening leading to 4,4-dichlorobutanamides. These compounds proved to be suitable substrates for the synthesis of 3-pyrrolin-2-ones, 2-pyrrolidinones, pyrrolidines and pyrroles.
