71861-76-2 Usage
Chemical class
Fluorouracil derivative
Molecular structure
Fluorinated pyrimidine analog
Anti-cancer properties
Potential antitumor and anticancer activities
Relationship to 5-fluorouracil
Fluorinated derivative of the widely used anticancer medication
Structural modification
Addition of an acetyl and toluyl group to the 5-fluorouracil molecule
Purpose of modification
To enhance pharmacological properties and increase effectiveness in targeting cancer cells
Research findings
Exhibits promising antitumor activity in various cancer cell lines
Current status
Being evaluated as a potential treatment option for different types of cancer
Check Digit Verification of cas no
The CAS Registry Mumber 71861-76-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,6 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 71861-76:
(7*7)+(6*1)+(5*8)+(4*6)+(3*1)+(2*7)+(1*6)=142
142 % 10 = 2
So 71861-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H11FN2O4/c1-8-5-3-4-6-10(8)12(19)17-13(20)11(15)7-16(9(2)18)14(17)21/h3-7H,1-2H3
71861-76-2Relevant academic research and scientific papers
Studies on the Synthesis of Chemotherapeutics. 10. Synthesis and Antitumor Activity of N-Acyl- and N-(Alkoxycarbonyl)-5-fluorouracil Derivatives
Kametani, Tetsuji,Kigasawa, Kazuo,Hiiragi, Mineharu,Wakisaka, Kikuo,Haga, Seiji,et al.
, p. 1324 - 1329 (2007/10/02)
A number of N-acyl and N-(alkoxycarbonyl)-5-fluorouracil derivatives possessing for example, benzoyl, o-toluyl, acetyl, propionyl, heptanoyl, etoxycarbonyl, phenoxycarbonyl, and benzyloxycarbonyl groups as N1 and/or N3 substituents w
