718639-57-7

Basic information

• Product Name: 2-Chloro-4-isopropoxy-pyridine
• Synonyms: 2-Chloro-4-isopropoxy-pyridine
• CAS NO: 718639-57-7
• Molecular Formula: C8H10ClNO
• Molecular Weight: 171.626
• Mol File: 718639-57-7.mol

Chemical Properties

• CAS DataBase Reference: 2-Chloro-4-isopropoxy-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-isopropoxy-pyridine(718639-57-7)
• EPA Substance Registry System: 2-Chloro-4-isopropoxy-pyridine(718639-57-7)

Safety Data

• Hazardous Substances Data: 718639-57-7(Hazardous Substances Data)

Upstream product

• 17368-12-6 2-chloropyridin-4-ol 
• 75-30-9 2-iodo-propane 
• 23056-36-2 2-chloro-4-nitropyridine 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 718639-62-4 4-{2-[methyl(4-isopropoxypyridin-2-yl)amino]ethoxy}benzaldehyde 

Relevant articles and documents

PYRROLIDINE OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to pyrrolidine compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.

Synthesis and biological activity of novel substituted pyridines and purines containing 2,4-thiazolidinedione

A series of substituted pyridines and purines containing 2,4-thiazolidinedione were designed and synthesized from their corresponding pyridines and purines. These synthesized compounds (entry no. 6a-d, 12a-e, 18a-d, 23a-c) were evaluated for their effect on triglyceride accumulation in 3T3-L1 cells in vitro and their hypoglycemic and hypolipidemic activity in the genetically diabetic KKAy mice in vivo. On the basis of their biological activities, 5-(4-{2-[N-methyl-(5-phenyl-pyridin-2-yl)amino]ethoxy} benzyl)thiazolidine-2,4-dione (6d) was selected as a candidate for further pharmacological studies.