7187-66-8 Usage
Uses
Used in Pharmaceutical Industry:
Trimethaphan is used as an antihypertensive agent for managing high blood pressure. It works by inhibiting the angiotensin-converting enzyme (ACE), which helps in reducing the peripheral vascular resistance and, consequently, lowering the blood pressure. This makes it a valuable drug for patients suffering from hypertension.
Clinical Use
Trimethaphan camsylate (Arfonad) is an extremely
short-acting agent whose major therapeutic use is in the
production of controlled hypotension in certain surgical procedures and in the emergency treatment of hypertensive
crisis. Continuous infusion may be employed to
maintain its antihypertensive effect, especially in patients
with an acute dissecting aortic aneurysm. Much of
the decrease in blood pressure following trimethaphan
administration is thought to be due to its direct vasodilating
properties.
Trimethaphan can produce prolonged neuromuscular
blockade in some patients, and therefore, it
should be used with caution as a hypotensive agent
during surgery. It also has been reported to potentiate
the neuromuscular blocking action of tubocurarine,
and because of its histamine-releasing properties,
trimethaphan should be used with caution in patients
with allergies.
Check Digit Verification of cas no
The CAS Registry Mumber 7187-66-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,8 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7187-66:
(6*7)+(5*1)+(4*8)+(3*7)+(2*6)+(1*6)=118
118 % 10 = 8
So 7187-66-8 is a valid CAS Registry Number.
