7188-94-5

Usage

Class

Aromatic heterocyclic compounds containing a five-membered ring with two nitrogen atoms and three carbon atoms

Structure

A derivative of pyrazole with a methyl group at the 3-position and two phenyl groups at the 1 and 4 positions

Usage

Building block in the synthesis of various pharmaceuticals and agrochemicals

Reactivity

Versatile

Functional group compatibility

High

Biological activities

Exhibits interesting biological activities

Importance in pharmaceutical industry

Valuable intermediate

Upstream product

• 506437-31-6 C₂₀H₂₄N₂ 
• 100-63-0 phenylhydrazine 
• 103-26-4 methyl cinnamate 
• 87839-77-8 3-Methyl-1,4-diphenylpyrazol-5-carbonsaeure-methylester 
• 87839-76-7 3-Methyl-1,4-diphenyl-2-pyrazolin-5-carbonsaeure-methylester 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 118559-38-9 N-(1-Nitroethylidene)-N'-phenyl-N'-sodiohydrazine 
• 22706-20-3 5-methyl-2-phenyl-2H-tetrazole 
• 79481-69-9 1,4-diphenyl-3-methyl-5-pyrazolone 
• 7789-60-8 phosphorus tribromide 
• 93323-68-3 3-Methyl-1,4-diphenylpyrazol-5-carbonsaeure 

Relevant academic research and scientific papers

Pyrazole synthesis using a titanium-catalyzed multicomponent coupling reaction and synthesis of withasomnine

The titanium-catalyzed 3-component coupling of an alkyne, isonitrile, and amine can be used to generate tautomers of 1,3-diimines. These diimines produced in situ undergo cyclization with hydrazine and hydrazine derivatives in a one-pot procedure to provi

1,3-Dipolar Cycloadditions, 88. C-Methyl-N-phenylnitrilimine and the Regiochemistry of its Cycloadditions

The title compound, a representative of the little known C-alkylnitrilimines, is accessible by three routes: NaNO2 elimination from sodium (α-nitroethylidene)phenylhydrazine in boiling acetonitrile, photolysis of 5-methyl-2-phenyltetrazole, and the thermo