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1H-Pyrazole-3-methanol, 1-phenyl- is an organic compound with the molecular formula C10H11NO. It is a derivative of pyrazole, a five-membered heterocyclic ring containing one nitrogen atom and one oxygen atom. The 1-phenyl substitution indicates the presence of a phenyl group (C6H5) attached to the nitrogen atom at the first position of the pyrazole ring. 1H-Pyrazole-3-methanol, 1-phenyl- is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, as well as its use as an intermediate in the preparation of other organic compounds. Its chemical structure and properties make it a versatile building block in organic synthesis, particularly in the development of new drugs and chemical compounds.

7189-08-4

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7189-08-4 Usage

Class

Pyrazole derivatives

Type of compound

Organic compound

Common uses

Building block for the synthesis of various drugs and pesticides in the pharmaceutical and agrochemical industries

Potential biological activities

Effects on the central nervous system

Industrial applications

Potential use as a corrosion inhibitor

Check Digit Verification of cas no

The CAS Registry Mumber 7189-08-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,8 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7189-08:
(6*7)+(5*1)+(4*8)+(3*9)+(2*0)+(1*8)=114
114 % 10 = 4
So 7189-08-4 is a valid CAS Registry Number.

7189-08-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (1-phenyl-1H-pyrazol-3-yl)-methanol

1.2 Other means of identification

Product number -
Other names 1-Phenyl-3-hydroxymethyl-pyrazol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7189-08-4 SDS

7189-08-4Relevant academic research and scientific papers

Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl) methanamines as potent and efficacious type II calcimimetics

Poon, Steve F.,St Jean Jr., David J.,Harrington, Paul E.,Henley III, Charles,Davis, James,Morony, Sean,Lott, Fred D.,Reagan, Jeff D.,Lu, Jenny Ying-Lin,Yang, Yuhua,Fotsch, Christopher

supporting information; experimental part, p. 6535 - 6538 (2010/04/03)

Our efforts to discover potent, orally bioavailable type II calcimimetic agents for the treatment of secondary hyperparathyroidism focused on the development of ring constrained analogues of the known calcimimetic R-568. The structure-activity relationships of various substituted heterocycles and their effects on the human calcium-sensing receptor are discussed. Pyrazole 15 was shown to be efficacious in a rat in vivo pharmacodynamic model.

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