71916-71-7Relevant academic research and scientific papers
SPIROPIPERIDINE DERIVATIVES
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, (2018/07/05)
Described herein are spiropiperidine compounds according to Formula I that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described spiropiperidine compounds, and methods
MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS
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, (2015/05/26)
The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.
HISTAMINE H3 INVERSE AGONISTS AND ANTAGONISTS AND METHODS OF USE THEREOF
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Page/Page column 128, (2010/12/29)
Provided herein are spiro-cyclic compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, including, e.g., neurological disorders and metab
Synthesis of 2,3-Dihydrospiro and 2,3-dihydrospiro
Effland, Richard C.,Gardner, Beth Ann,Strupczewski, Joseph
, p. 811 - 814 (2007/10/02)
The synthesis of 2,3-dihydrospiro 3 and 2,3-dihydrospiro 6 is described.The synthesis was achieved by a Grignard reaction of a 2-fluorobenzylhalide with an appropriate cycloazaalkyl ketone to yield
