71916-73-9

Usage

Uses

Used in Pharmaceutical Industry:
3H-SPIRO[1-BENZOFURAN-2,4''-PIPERIDINE] is used as a molecular scaffold for the design and synthesis of new bioactive molecules due to its unique spiro ring system and the presence of pharmacophoric benzofuran and piperidine moieties. 3H-SPIRO[1-BENZOFURAN-2,4''-PIPERIDINE] serves as a promising candidate in drug discovery, potentially leading to the development of novel therapeutic agents.
Used in Drug Discovery and Development:
3H-SPIRO[1-BENZOFURAN-2,4''-PIPERIDINE] is utilized as a starting point for creating new pharmaceutical compounds with potential applications in treating various diseases and medical conditions. Its structural and biological properties make it a valuable asset in the search for innovative drug candidates that can address unmet medical needs.
Used in Research and Development:
In the field of medicinal chemistry, 3H-SPIRO[1-BENZOFURAN-2,4''-PIPERIDINE] is employed as a subject of study to understand its chemical properties and explore its potential biological activities. This research can contribute to the advancement of knowledge in drug design and the identification of new therapeutic targets.

Upstream product

• 4783-65-7 N-benzyl-2-piperidinone 
• 345-35-7 2-fluorobenzyl chloride 
• 71916-70-6 1-benzyl-4-(2-fluorobenzyl)-4-hydroxypiperidine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 71916-71-7 1'-benzyl-2,3-dihydrospiro 

Downstream Products

• 91830-17-0 5-bromo-2,3-dihydro-spiro[benzofuran-2(3H),4'-piperidine] 
• 644970-18-3 4-fluoro-2-{[(2S)-2-hydroxy-3-(1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)propyl]oxy}benzoic acid hydrochloride 
• 1427190-13-3 C₃₄H₄₇N₃O₈ 
• 1427190-07-5 C₂₄H₃₁N₃O₄ 
• 71918-12-2 2,3-dihydro-1'-(3,4,5-trimethoxybenzoyl)spiro[benzofuran-2,4'-piperidine] 
• 71918-11-1 2,3-dihydro-1'-(3-phenoxypropyl)spiro[benzofuran-2,4'-piperidine]hydrochloride 
• 71918-05-3 2,3-dihydro-1'-[(4-methoxyphenyl)acetyl]spiro[benzofuran-2,4'-piperidine] 
• 71916-75-1 2,3-dihydro-1'-[3-(4-fluorobenzoyl)propyl]spiro[benzofuran-2,4'-piperidine]hydrochloride 

Relevant academic research and scientific papers

SPIROPIPERIDINE DERIVATIVES

Described herein are spiropiperidine compounds according to Formula I that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described spiropiperidine compounds, and methods

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.

HISTAMINE H3 INVERSE AGONISTS AND ANTAGONISTS AND METHODS OF USE THEREOF

Provided herein are spiro-cyclic compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, including, e.g., neurological disorders and metab

1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]

This invention relates to 1'-[3-(1,2-benzisoxazol-3-yl)propyl]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines] of the formula: STR1 where X and Y are the same or different and are hydrogen, halogen, lower alkoxy, lower alkyl, nitro, hydroxy

Synthesis of 2,3-Dihydrospiro and 2,3-dihydrospiro

The synthesis of 2,3-dihydrospiro 3 and 2,3-dihydrospiro 6 is described.The synthesis was achieved by a Grignard reaction of a 2-fluorobenzylhalide with an appropriate cycloazaalkyl ketone to yield

Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines

Novel Spiro[dihydrobenzofuran-piperidine and pyrrolidine]s and methods of preparing same are described. These compounds are useful as analgetics and tranquilizers and as intermediates.

Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines

Novel N-[3-benzoylpropyl]spiro[dihydrobenzofuran-piperidine and pyrrolidine]s and methods of preparing same are described. These compounds are useful as analgetics and tranquilizers.