71920-45-1Relevant academic research and scientific papers
A catalytic multicomponent protocol to dihydropyridine-3-carboxylate from terminal alkynes, isocyanates, and malonates
Beigi-Somar, Vahid,Homami, Seyed Saied,Ghazanfarpour-Darjani, Majid,Monzavi, Amirhossein
, p. 231 - 241 (2020)
Abstract: A domino catalytic reaction between terminal alkynes, isocyanates, and malonates has been developed. Copper acetylides attack on isocyanates to form a propargylic amide species which further reacted with malonates by the action of t-BuOLi to for
