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Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B. It is known for its inhibitory effects on various biological processes, including prostaglandin biosynthesis and glucose-6-phosphatase activity.
Used in Pharmaceutical Industry:
Thielavin A is used as a glucose-6-phosphatase inhibitor for its ability to inhibit glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 μM), which can be beneficial in the development of treatments for certain metabolic disorders.
Used in Anti-inflammatory Applications:
Thielavin A is used as an inhibitor of prostaglandin biosynthesis for its ability to block the conversion of arachidonic acid to prostaglandin H2 (PGH2) and the conversion of PGH2 to PGE2 (IC50s = 10 and 40 μM, respectively), making it a potential candidate for the development of anti-inflammatory drugs.
Used in Enzyme Inhibition Research:
Thielavin A is used as a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC50 = 23.8 μM; Ki = 27.8 μM) for its potential applications in studying enzyme inhibition mechanisms and developing new therapeutic agents targeting specific enzymes.

71950-66-8

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71950-66-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 71950-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,9,5 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 71950-66:
(7*7)+(6*1)+(5*9)+(4*5)+(3*0)+(2*6)+(1*6)=138
138 % 10 = 8
So 71950-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C29H30O10/c1-10-9-18(30)15(6)22(31)19(10)28(36)38-26-14(5)12(3)21(24(33)17(26)8)29(37)39-25-13(4)11(2)20(27(34)35)23(32)16(25)7/h9,30-33H,1-8H3,(H,34,35)

71950-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[4-(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,5,6-trimethylbenzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoic acid

1.2 Other means of identification

Product number -
Other names Thielavin A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71950-66-8 SDS

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