71978-57-9Relevant academic research and scientific papers
3-substituted-aminomethyl cephalosporin derivatives
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, (2008/06/13)
A cephalosporin derivative of the formula I: STR1 in which X is S, O, CH2 or SO, R1 is (optionally-substituted)imidazol-2-yl or one of the C-7 acyl groups known in the cephalosporin art, R2 is hydrogen or methoxy, R3 is carboxy or a biodegradable ester thereof and --R4 is of the formula XII, XIII or XIV: STR2 in which R32-R40 inclusive are as defined in the specification; and the salts thereof. Pharmaceutical compositions, methods of manufacture and intermediates are also described.
