72004-64-9Relevant academic research and scientific papers
Nickel-catalyzed ring-opening cross-coupling of cyclic alkenyl ethers with arylboronic esters via carbon-oxygen bond cleavage
Ohtsuki, Akimichi,Sakurai, Shun,Tobisu, Mamoru,Chatani, Naoto
supporting information, p. 1277 - 1279 (2016/11/09)
We have developed a nickel-catalyzed cross-coupling reaction of cyclic alkenyl ethers with arylboronic esters that leads to the formation of unsaturated alcohols via ring-opening by the cleavage of a C(sp2)-O bond. The use of 1,3-dicyclohexylimidazol-2-ylidene as the ligand is essential to promote this cross-coupling process.
Chemo-, regio-, and stereoselective Heck-Matsuda arylation of allylic alcohols under mild conditions
Chaudhari, Tohasib Yusub,Hossian, Asik,Manna, Manash Kumar,Jana, Ranjan
supporting information, p. 4841 - 4845 (2015/05/05)
Heck arylation with allylic alcohol is extremely challenging due to chemo-, regio-, and stereoselective scrambling. Here we report a mild protocol for the alcohol selective β- and α-arylation of allylic and cinnamyl alcohols respectively with aryldiazonium salts. The steric and electronic parameters of the alkene play a prominent role in the regioselectivity.
