72007-46-6Relevant academic research and scientific papers
Development of strong Bronsted base catalysis: Catalytic direct-type Mannich reactions of non-activated esters via a product-base mechanism
Yamashita, Yasuhiro,Suzuki, Hirotsugu,Kobayashi, Shu
supporting information; body text, p. 5750 - 5752 (2012/08/28)
A catalytic Mannich reaction of a simple ester with no activating functionality at the α-position via a product-base mechanism was reported. The desired Mannich adducts were obtained in high yields using a catalytic amount of KH. This is a rare example of
