72008-35-6Relevant academic research and scientific papers
Novel synthesis method of intermediate C15 alcohol for preparing canthaxanthin
-
Paragraph 0022; 0026; 0043-0045; 0055-0057, (2021/09/26)
The invention discloses a novel synthesis method of an intermediate C15 alcohol for preparing canthaxanthin. The synthesis method comprises the following steps: 1) under the protection of inert gas, adding 4-oxo-beta-violet ketone and an organic solvent into a reactor, performing stirring and dissolving, and dropwise adding a vinyl Grignard reagent; 2) after dropwise adding, dropwise adding protonic acid for hydrolysis; and 3) after standing and layering, removing a water phase, and concentrating and distilling an organic phase, so as to obtain 3-[3-hydroxy-3-methyl-pent-1,4-dienyl]-2,4,4-trimethyl-cyclohex-2-ene-1-ketone. The synthesis route has the advantages of low raw material price, few reaction steps, mild reaction conditions, no need of a catalyst, environmental friendliness, convenience in operation and high reaction yield.
Preparation of a 1,4-pentadien-3-ol
-
, (2008/06/13)
A new process for preparing 1-(3-oxo-2,6,6-trimethyl-1-cyclohexen-1-yl)-3-methyl-1,4-pentadien-3-ol, a intermediate for canthaxanthin, from hydroxy-β-ionone.
1-(2,6,6-Trimethyl-3-hydroxy-1-cyclohexen-1-yl)-3-methyl-penta-1,4-diene[or 1-yn-4-EN]-3-ols
-
, (2008/06/13)
A total synthesis of canthaxanthin, a known food coloring agent from alpha or retro ionone.
