72011-31-5Relevant academic research and scientific papers
IDH1 mutant micromolecule inhibitor, and preparation method and application thereof
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Paragraph 0216-0218, (2019/07/16)
The invention discloses an IDH1 mutant micromolecule inhibitor, and a preparation method and application thereof. The structure of the inhibitor is as shown in a formula I, and the definition of the substituent groups is as described in the specification
β-Enamino esters in heterocyclic synthesis: Synthesis of pyrazolone and pyridinone derivatives
Salaheldin, Abdellatif Mohamed,Al-Sheikh, Mariam Abdullah
experimental part, p. 4359 - 4368 (2010/10/01)
An efficient and convenient synthesis of pyrrolidinones and pyridinones utilizing enamino esters as starting material has been described. The structures of the compounds obtained were confirmed by spectral and elemental analyses.
Reaction of Singlet Oxygen with Enamino Carbonyl Systems. A General Method for the Synthesis of α-Keto Derivatives of Lactones, Esters, Amides, Lactams, and Ketones
Wasserman, Harry H.,Ives, Jeffrey L.
, p. 3573 - 3580 (2007/10/02)
A general method for the introduction of a ketone α to the carbonyl group of a ketone, lactone. ester, substituted amide, or lactam has been developed involving the formation and dye-sensitized photooxygenation of enamino carbonyl intermediates.
REACTION OF GOLD'S REAGENT WITH ACTIVATED METHYLENE GROUPS DERIVED FROM ESTERS AND NITROARENES
Gupton, John T.,Lizzi, Michael J.,Polk, Dale
, p. 939 - 946 (2007/10/02)
A series of esters and nitrotoluenes were reacted with Gold's reagent under basic conditions and were found to produce the corresponding dimethylamino methyleneated product in both cases.
