72025-18-4Relevant academic research and scientific papers
Libraries via Metathesis of Internal Olefins
Braendli, Christof,Ward, Thomas R.
, p. 1616 - 1621 (2007/10/03)
The cross-metathesis of internal olefins is applied for the combinatorial synthesis of small organic molecules; this reaction is conveniently carried out in neat olefin (oleic-acid derivatives) and requires only 0.001 equiv. of [Ru(CHPh)Cl2(PCy3)2] as catalyst (Cy = cyclohexyl).
COMETATHESIS OF METHYL OLEATE WITH α-OLEFINS
Matyska, Bohumir,Dosedlova, Alena,Petrusova, Lidmila,Balcar, Hynek
, p. 455 - 461 (2007/10/02)
Cometathesis of methyl oleate with 1-hexene or with other α-olefins affords two new esters and two new olefins.In the case of 1-hexene these products are methyl 9-decenoate, methyl 9-tetradecenoate, 1-decene and 5-tetradecene.At the same time, the formation of the esters and olefins with shorter chains (i.e. decene and decenoate) is distinctly preferred.Obviously, the transfer of methylene group from the alkene to the ester molecule is much easier than that of the alkylidene moiety.The non-stoichiometric course of cometathesis is associated with the carbene mechanism of the reaction.
