72030-17-2

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-chlorophenyl)-3-(thiophen-2-yl)prop-2-enenitrile is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex molecular structures that can exhibit therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(4-chlorophenyl)-3-(thiophen-2-yl)prop-2-enenitrile is utilized as a precursor in the development of compounds that can be used in crop protection and pest management, leveraging its reactivity and structural features.
Used in Organic Compounds Synthesis:
2-(4-chlorophenyl)-3-(thiophen-2-yl)prop-2-enenitrile is employed as a building block for the preparation of various heterocyclic compounds, which are important in organic chemistry for their diverse applications and unique properties.
Used in Chemical Industry:
2-(4-chlorophenyl)-3-(thiophen-2-yl)prop-2-enenitrile is also used in the broader chemical industry as a versatile intermediate, contributing to the synthesis of a wide array of organic compounds for different applications, including but not limited to materials science, dyes, and specialty chemicals.

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 140-53-4 p-chlorobenzyl cyanide 
• 6258-63-5 (2-thienyl)methanethiol 

Relevant academic research and scientific papers

Direct C–S Bond Functionalization of Benzyl Mercaptan

Cleavage of a C–S bond of benzyl mercaptan led to formation of a new C–C bond during (Z)-selective alkenylation of nitriles using 1,10-phenanthroline as organocatalyst and tBuOK as a base. Furthermore, we have shown that the cascaded functionalization of benzylic C–S and aryl–halide bonds could be done in one pot. 1H NMR study and kinetic experiments also helped to establish the mechanism of the reaction.

Fungicidal 2-aryl-2-cyano-2-(heterocyclylalkyl)ethyl-1,2,4-triazoles

This invention relates to 2-aryl-2-cyano-2-(heterocyclylalkyl)ethyl-1,2,4-triazoles of the formula STR1 wherein Ar is an optionally substituted aryl group, Het is an optionally substituted five or six membered saturated or unsaturated heterocyclic ring containing one, two or three heteroatoms selected from oxygen, nitrogen and sulfur, or is a bicyclic unsaturated ring system containing up to ten atoms including one heteroatom selected from oxygen, nitrogen and sulfur, R is hydrogen or alkyl, n is zero or an integer of at least one, and the agronomically acceptable enantiomorphs, geometric isomers, acid addition salts and metal salt complexes thereof.

Kinetic Study of the Base-catalysed Reactions of Benzaldahehyde and Thiophene-2-carbaldehyde with Acetonitriles

The reaction rates of the sodium methoxide-catalysed condensation of benzaldehyde and thiophene-2-carbaldehyde with heteroaromatic acetonitriles ArCH2CN; Ar = C6H5, C6H4CH3(p), C6H4-OCH3(p), C6H4F(p), C6H4Cl(p), C6H4Br(p), 2-thienyl, 3-thienyl, 3-pyridyl