72035-78-0

Basic information

• Product Name: 8b-Methoxy-2,2-dimethyl-3-phenyl-1,2,2a,8b-tetrahydro-cyclobuta[a]naphthalene
• Synonyms: 8b-Methoxy-2,2-dimethyl-3-phenyl-1,2,2a,8b-tetrahydro-cyclobuta[a]naphthalene
• CAS NO: 72035-78-0
• Molecular Weight: 290.405
• Mol File: 72035-78-0.mol

Chemical Properties

• CAS DataBase Reference: 8b-Methoxy-2,2-dimethyl-3-phenyl-1,2,2a,8b-tetrahydro-cyclobuta[a]naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 8b-Methoxy-2,2-dimethyl-3-phenyl-1,2,2a,8b-tetrahydro-cyclobuta[a]naphthalene(72035-78-0)
• EPA Substance Registry System: 8b-Methoxy-2,2-dimethyl-3-phenyl-1,2,2a,8b-tetrahydro-cyclobuta[a]naphthalene(72035-78-0)

Safety Data

• Hazardous Substances Data: 72035-78-0(Hazardous Substances Data)

Upstream product

• 72035-61-1 2,2-Dimethyl-3-phenyl-2,2a-dihydro-1H-cyclobuta[a]naphthalen-8b-ol 
• 74-88-4 methyl iodide 
• 36047-17-3 5,5-dimethyl-3-phenyl-2-cyclohexen-1-one 

Relevant articles and documents

Arynic Condensations of Ketone Enolates. 15. New Synthetic Applications of the Condensation of α,β-Unsaturated Ketone Enolates on Benzyne

Arynic condensations of both cyclic and acyclic α,β-unsaturated ketone enolates are studied.First, condensation of substituted cyclohexenone enolates with benzyne leads to a new class of cyclobutanic alcohols 6.Ring opening of 6 under basic conditions is described as a good means of synthesizing benzocyclooctadienones 10 and 19, and, in appropriate cases, benzocyclooctenediones of type 12.Thermal dehydration of 6 affords 1,3-disubstituted naphthalenes in good yields.Second, condensations of a few acyclic α,β-unsaturated ketone enolates with benzyne are shown to be of synthetic usefulness; depending on the substituents on both sides of the carbonyl group, these condensations may lead either to substituted naphthalenes or to phenyl ketones or tetralones.