7205-69-8

Upstream product

• 5120-72-9 p-chlorophenyl ethyl sulfide 
• 74-96-4 ethyl bromide 
• 106-54-7 p-Chlorothiophenol 
• 64-17-5 ethanol 
• 3085-42-5 bis(4-chlorophenyl)sulfoxide 
• 557-18-6 diethylmagnesium 
• 97-93-8 triethylaluminum 
• 98-60-2 4-chlorobenzenesulfonyl chloride 

Downstream Products

• 127721-29-3 1-Chloro-4-(1-chloro-ethanesulfinyl)-benzene 
• 934-73-6 methyl 4-chlorophenyl sulfoxide 
• 7205-75-6 p-Chlorphenyl-1,1-dimethylaethylsulfoxid 
• 16411-16-8 p-chlorophenyl vinyl sulfide 

Relevant academic research and scientific papers

Tungstate supported on magnetic ionic liquid-modi?ed graphene oxide as an efficient and recyclable catalyst for the selective oxidation of sulfides

An effective and recyclable catalyst based on tungstate ion immobilization on magnetic ionic liquid modified graphene oxide (WO4@Fe3O4/GO-IL) has been synthesized in this research. The catalyst was characterized by various

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent

A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.

Kinetic investigation on the highly efficient and selective oxidation of sulfides to sulfoxides and sulfones with t-BuOOH catalyzed by La2O3

The selective oxidation of various sulfides to sulfoxides by a simple, efficient, and environmentally benign method is of prime focus. In this paper, we have explored a highly efficient protocol for the oxidation of alkyl aryl sulfides to sulfoxides with high selectivities catalyzed by La2O3 in the presence of 70% t-BuOOH solution (water). We obtained predominantly the monooxygenated product. The over oxidation of sulfides to sulfones was not observed under these conditions. The resulting products are obtained in good to excellent yields within a reasonable time without the use of ligands and other additives. The epoxidation of the double bond as well as allylic oxidation are not observed with allyl sulfides. Sulfones can be obtained quantitatively by altering the reaction conditions. The surface morphology and the catalyst reusability were verified by XRD, AFM and SEM techniques. The surface area of the La2O3 was measured using BET isotherms.

Symmetric diarylsulfoxides as asymmetric sulfinylating reagents for dialkylmagnesium compounds

At -78 °C, primary dialkylmagnesium compounds reacted with diarylsulfoxides when 1.5 equiv of the dilithium salt of (S)-BINOL was added as a promotor. Alkyl aryl sulfoxides resulted in up to quantitative yield and with up to 97% ee. This demonstrates the feasibility of asymmetric sulfinylations by achiral sulfinylating agents (from the perspective of Alkyl2Mg) as well as the feasibility of asymmetric sulfoxide-magnesium exchanges (from the perspective of Ar2SO).

Competing reaction pathways from α-halo-α-protioalkyl aryl sulfoxides initiated by organometallic reagents

The reactions of syn-1-haloethyl p-chlorophenyl sulfoxides (halogen = Cl, Br) with main-group organometallic reagents (n-BuMgCl, MeLi, n-BuLi, s-BuLi, and t-BuLi) in THF and PhMe solvents were examined. Product distributions were analyzed to determine the

Efficient and highly selective oxidation of sulfides to sulfoxides in the presence of an ionic liquid containing hypervalent iodine

A mild, efficient, highly selective, and environmentally friendly oxidation of sulfides to sulfoxides with a recyclable ion-supported hypervalent iodine reagent has been developed. This reaction is tolerant of hydroxyl, nitrile, methoxy, carbon-carbon double bonds, and ester functionalities. Aliphatic and aromatic sulfides are selectively oxidized to the corresponding sulfoxides at room temperature in excellent yields. Georg Thieme Verlag Stuttgart.

Iodic acid (HIO3) in combination with tetraethylammonium bromide as a catalyst for selective and accelerated sulfoxidation

The article describes the use of iodic acid in combination with catalytic amounts of tetraethylammonium bromide (TEAB) as a mild and alternative reagent system for oxidation of sulfides to sulfoxides. The salient features of the developed system are room-

Selective and efficient oxidation of sulfides to sulfoxides with N-bromosuccinimide in the presence of β-cyclodextrin in water

A simple and highly selective oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) catalyzed by β-cyclodextrin in water has been developed. A series of sulfides were oxidized selectively at room temperature in excellent yields. This reaction

A mild, chemoselective oxidation of sulfides to sulfoxides using o-iodoxybenzoic acid and tetraethylammonium bromide as catalyst

A mild, selective, and high-yielding method for oxidation of sulfides to sulfoxides using IBX and tetraethylammonium bromide in a variety of solvents is described. The method offers the advantage of short reaction times, no over-oxidation to sulfones, and compatibility to a wide range of functional groups.

Hypervalent iodine in synthesis. XXIII: Oxidation with [hydroxy(tosyloxy)iodo]benzene: Selective oxidation of sulfides to sulfoxides

Alkyl- and aryl-sulfides can be selectively oxidated to their corresponding sulfoxides with excellent yields under mild conditions by [hydroxy(tosyloxy)iodo]benzene. Moreover, [hydroxy (((+)-10-camphorosulfonyl)oxy)iodo]benzene as the chiral oxidizer, can